Sampson JR - Search Results

1

Assessment of Response of Kidney Tumors to Rapamycin and Atorvastatin in Tsc1^+/- Mice.

Shen MH, Samsel P, Shen LL, Narov K, Yang J, Sampson JR. Shen MH, et al. Among authors: sampson jr. Transl Oncol. 2017 Oct;10(5):793-799. doi: 10.1016/j.tranon.2017.07.009. Epub 2017 Aug 24. Transl Oncol. 2017. PMID: 28844017 Free PMC article.

2

T2 weighted MRI for assessing renal lesions in transgenic mouse models of tuberous sclerosis.

Kalogerou M, Zhang Y, Yang J, Garrahan N, Paisey S, Tokarczuk P, Stewart A, Gallacher J, Sampson JR, Shen MH. Kalogerou M, et al. Among authors: sampson jr. Eur J Radiol. 2012 Sep;81(9):2069-74. doi: 10.1016/j.ejrad.2011.06.054. Epub 2011 Jul 28. Eur J Radiol. 2012. PMID: 21802234

3

Renal tumours in a Tsc1+/- mouse model show epigenetic suppression of organic cation transporters Slc22a1, Slc22a2 and Slc22a3, and do not respond to metformin.

Yang J, Kalogerou M, Gallacher J, Sampson JR, Shen MH. Yang J, et al. Among authors: sampson jr. Eur J Cancer. 2013 Apr;49(6):1479-90. doi: 10.1016/j.ejca.2012.10.027. Epub 2012 Dec 7. Eur J Cancer. 2013. PMID: 23228442

4

Renal tumours in a Tsc2(+/-) mouse model do not show feedback inhibition of Akt and are effectively prevented by rapamycin.

Yang J, Kalogerou M, Samsel PA, Zhang Y, Griffiths DF, Gallacher J, Sampson JR, Shen MH. Yang J, et al. Among authors: sampson jr. Oncogene. 2015 Feb 12;34(7):922-31. doi: 10.1038/onc.2014.17. Epub 2014 Mar 17. Oncogene. 2015. PMID: 24632604

5

mTORC1 drives HIF-1α and VEGF-A signalling via multiple mechanisms involving 4E-BP1, S6K1 and STAT3.

Dodd KM, Yang J, Shen MH, Sampson JR, Tee AR. Dodd KM, et al. Among authors: sampson jr. Oncogene. 2015 Apr 23;34(17):2239-50. doi: 10.1038/onc.2014.164. Epub 2014 Jun 16. Oncogene. 2015. PMID: 24931163 Free PMC article.

6

Combination of Everolimus with Sorafenib for Solid Renal Tumors in Tsc2^+/- Mice Is Superior to Everolimus Alone.

Yang J, Samsel PA, Narov K, Jones A, Gallacher D, Gallacher J, Sampson JR, Shen MH. Yang J, et al. Among authors: sampson jr. Neoplasia. 2017 Feb;19(2):112-120. doi: 10.1016/j.neo.2016.12.008. Epub 2017 Jan 13. Neoplasia. 2017. PMID: 28092822 Free PMC article.

7

The dual PI3K/mTOR inhibitor GSK2126458 is effective for treating solid renal tumours in Tsc2^+/- mice through suppression of cell proliferation and induction of apoptosis.

Narov K, Yang J, Samsel P, Jones A, Sampson JR, Shen MH. Narov K, et al. Among authors: sampson jr. Oncotarget. 2017 Apr 19;8(35):58504-58512. doi: 10.18632/oncotarget.17215. eCollection 2017 Aug 29. Oncotarget. 2017. PMID: 28938574 Free PMC article.

8

Loss of tuberous sclerosis complex 2 sensitizes tumors to nelfinavir-bortezomib therapy to intensify endoplasmic reticulum stress-induced cell death.

Johnson CE, Dunlop EA, Seifan S, McCann HD, Hay T, Parfitt GJ, Jones AT, Giles PJ, Shen MH, Sampson JR, Errington RJ, Davies DM, Tee AR. Johnson CE, et al. Among authors: sampson jr. Oncogene. 2018 Nov;37(45):5913-5925. doi: 10.1038/s41388-018-0381-2. Epub 2018 Jul 6. Oncogene. 2018. PMID: 29980790

9

Efficacy of Dual Inhibition of Glycolysis and Glutaminolysis for Therapy of Renal Lesions in Tsc2^+/- Mice.

Jones AT, Narov K, Yang J, Sampson JR, Shen MH. Jones AT, et al. Among authors: sampson jr. Neoplasia. 2019 Feb;21(2):230-238. doi: 10.1016/j.neo.2018.12.003. Epub 2019 Jan 8. Neoplasia. 2019. PMID: 30622053 Free PMC article.

10

Correction: Loss of tuberous sclerosis complex 2 sensitizes tumors to nelfinavir-bortezomib therapy to intensify endoplasmic reticulum stress-induced cell death.

Johnson CE, Dunlop EA, Seifan S, McCann HD, Hay T, Parfitt GJ, Jones AT, Giles PJ, Shen MH, Sampson JR, Errington RJ, Davies DM, Tee AR. Johnson CE, et al. Among authors: sampson jr. Oncogene. 2019 Apr;38(16):3102. doi: 10.1038/s41388-018-0598-0. Oncogene. 2019. PMID: 30622341 Free PMC article.

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