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An aberrant NOTCH2-BCR signaling axis in B cells from patients with chronic GVHD.
Poe JC, Jia W, Su H, Anand S, Rose JJ, Tata PV, Suthers AN, Jones CD, Kuan PF, Vincent BG, Serody JS, Horwitz ME, Ho VT, Pavletic SZ, Hakim FT, Owzar K, Zhang D, Blazar BR, Siebel CW, Chao NJ, Maillard I, Sarantopoulos S. Poe JC, et al. Among authors: siebel cw. Blood. 2017 Nov 9;130(19):2131-2145. doi: 10.1182/blood-2017-05-782466. Epub 2017 Aug 29. Blood. 2017. PMID: 28851699 Free PMC article. Clinical Trial.
Blockade of individual Notch ligands and receptors controls graft-versus-host disease.
Tran IT, Sandy AR, Carulli AJ, Ebens C, Chung J, Shan GT, Radojcic V, Friedman A, Gridley T, Shelton A, Reddy P, Samuelson LC, Yan M, Siebel CW, Maillard I. Tran IT, et al. Among authors: siebel cw. J Clin Invest. 2013 Apr;123(4):1590-604. doi: 10.1172/JCI65477. J Clin Invest. 2013. PMID: 23454750 Free PMC article.
Transient blockade of delta-like Notch ligands prevents allograft rejection mediated by cellular and humoral mechanisms in a mouse model of heart transplantation.
Wood S, Feng J, Chung J, Radojcic V, Sandy-Sloat AR, Friedman A, Shelton A, Yan M, Siebel CW, Bishop DK, Maillard I. Wood S, et al. Among authors: siebel cw. J Immunol. 2015 Mar 15;194(6):2899-908. doi: 10.4049/jimmunol.1402034. Epub 2015 Feb 16. J Immunol. 2015. PMID: 25687759 Free PMC article.
Developing HSCs become Notch independent by the end of maturation in the AGM region.
Souilhol C, Lendinez JG, Rybtsov S, Murphy F, Wilson H, Hills D, Batsivari A, Binagui-Casas A, McGarvey AC, MacDonald HR, Kageyama R, Siebel C, Zhao S, Medvinsky A. Souilhol C, et al. Blood. 2016 Sep 22;128(12):1567-77. doi: 10.1182/blood-2016-03-708164. Epub 2016 Jul 15. Blood. 2016. PMID: 27421959 Free PMC article.
NOTCH1 and NOTCH2 regulate epithelial cell proliferation in mouse and human gastric corpus.
Demitrack ES, Gifford GB, Keeley TM, Horita N, Todisco A, Turgeon DK, Siebel CW, Samuelson LC. Demitrack ES, et al. Among authors: siebel cw. Am J Physiol Gastrointest Liver Physiol. 2017 Feb 1;312(2):G133-G144. doi: 10.1152/ajpgi.00325.2016. Epub 2016 Dec 8. Am J Physiol Gastrointest Liver Physiol. 2017. PMID: 27932500 Free PMC article.
Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands.
Chung J, Ebens CL, Perkey E, Radojcic V, Koch U, Scarpellino L, Tong A, Allen F, Wood S, Feng J, Friedman A, Granadier D, Tran IT, Chai Q, Onder L, Yan M, Reddy P, Blazar BR, Huang AY, Brennan TV, Bishop DK, Ludewig B, Siebel CW, Radtke F, Luther SA, Maillard I. Chung J, et al. Among authors: siebel cw. J Clin Invest. 2017 Apr 3;127(4):1574-1588. doi: 10.1172/JCI89535. Epub 2017 Mar 20. J Clin Invest. 2017. PMID: 28319044 Free PMC article.
71 results