Helleday T - Search Results

1

Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer.

Asim M, Tarish F, Zecchini HI, Sanjiv K, Gelali E, Massie CE, Baridi A, Warren AY, Zhao W, Ogris C, McDuffus LA, Mascalchi P, Shaw G, Dev H, Wadhwa K, Wijnhoven P, Forment JV, Lyons SR, Lynch AG, O'Neill C, Zecchini VR, Rennie PS, Baniahmad A, Tavaré S, Mills IG, Galanty Y, Crosetto N, Schultz N, Neal D, Helleday T. Asim M, et al. Among authors: helleday t. Nat Commun. 2017 Aug 29;8(1):374. doi: 10.1038/s41467-017-00393-y. Nat Commun. 2017. PMID: 28851861 Free PMC article.

2

Different roles for nonhomologous end joining and homologous recombination following replication arrest in mammalian cells.

Lundin C, Erixon K, Arnaudeau C, Schultz N, Jenssen D, Meuth M, Helleday T. Lundin C, et al. Among authors: helleday t. Mol Cell Biol. 2002 Aug;22(16):5869-78. doi: 10.1128/MCB.22.16.5869-5878.2002. Mol Cell Biol. 2002. PMID: 12138197 Free PMC article.

3

RAD51 is involved in repair of damage associated with DNA replication in mammalian cells.

Lundin C, Schultz N, Arnaudeau C, Mohindra A, Hansen LT, Helleday T. Lundin C, et al. Among authors: helleday t. J Mol Biol. 2003 May 2;328(3):521-35. doi: 10.1016/s0022-2836(03)00313-9. J Mol Biol. 2003. PMID: 12706714

4

Poly(ADP-ribose) polymerase (PARP-1) has a controlling role in homologous recombination.

Schultz N, Lopez E, Saleh-Gohari N, Helleday T. Schultz N, et al. Among authors: helleday t. Nucleic Acids Res. 2003 Sep 1;31(17):4959-64. doi: 10.1093/nar/gkg703. Nucleic Acids Res. 2003. PMID: 12930944 Free PMC article.

5

p53 protects from replication-associated DNA double-strand breaks in mammalian cells.

Kumari A, Schultz N, Helleday T. Kumari A, et al. Among authors: helleday t. Oncogene. 2004 Mar 25;23(13):2324-9. doi: 10.1038/sj.onc.1207379. Oncogene. 2004. PMID: 14743204

6

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase.

Bryant HE, Schultz N, Thomas HD, Parker KM, Flower D, Lopez E, Kyle S, Meuth M, Curtin NJ, Helleday T. Bryant HE, et al. Among authors: helleday t. Nature. 2005 Apr 14;434(7035):913-7. doi: 10.1038/nature03443. Nature. 2005. PMID: 15829966 Free article.

7

Poly(ADP-ribose) polymerase (PARP-1) in homologous recombination and as a target for cancer therapy.

Helleday T, Bryant HE, Schultz N. Helleday T, et al. Cell Cycle. 2005 Sep;4(9):1176-8. doi: 10.4161/cc.4.9.2031. Epub 2005 Sep 12. Cell Cycle. 2005. PMID: 16123586 Review.

8

Mitotic defects in XRCC3 variants T241M and D213N and their relation to cancer susceptibility.

Lindh AR, Rafii S, Schultz N, Cox A, Helleday T. Lindh AR, et al. Among authors: helleday t. Hum Mol Genet. 2006 Apr 1;15(7):1217-24. doi: 10.1093/hmg/ddl037. Epub 2006 Feb 27. Hum Mol Genet. 2006. PMID: 16505003

9

RAD51C (RAD51L2) is involved in maintaining centrosome number in mitosis.

Renglin Lindh A, Schultz N, Saleh-Gohari N, Helleday T. Renglin Lindh A, et al. Among authors: helleday t. Cytogenet Genome Res. 2007;116(1-2):38-45. doi: 10.1159/000097416. Cytogenet Genome Res. 2007. PMID: 17268176

10

Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair.

Petermann E, Orta ML, Issaeva N, Schultz N, Helleday T. Petermann E, et al. Among authors: helleday t. Mol Cell. 2010 Feb 26;37(4):492-502. doi: 10.1016/j.molcel.2010.01.021. Mol Cell. 2010. PMID: 20188668 Free PMC article.

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