Murphy J - Search Results

1

Intermittent fasting preserves beta-cell mass in obesity-induced diabetes via the autophagy-lysosome pathway.

Liu H, Javaheri A, Godar RJ, Murphy J, Ma X, Rohatgi N, Mahadevan J, Hyrc K, Saftig P, Marshall C, McDaniel ML, Remedi MS, Razani B, Urano F, Diwan A. Liu H, et al. Among authors: murphy j. Autophagy. 2017;13(11):1952-1968. doi: 10.1080/15548627.2017.1368596. Epub 2017 Nov 25. Autophagy. 2017. PMID: 28853981 Free PMC article.

2

Tumor necrosis factor receptor-associated factor 2 mediates mitochondrial autophagy.

Yang KC, Ma X, Liu H, Murphy J, Barger PM, Mann DL, Diwan A. Yang KC, et al. Among authors: murphy j. Circ Heart Fail. 2015 Jan;8(1):175-87. doi: 10.1161/CIRCHEARTFAILURE.114.001635. Epub 2014 Oct 22. Circ Heart Fail. 2015. PMID: 25339503 Free PMC article.

3

Regulation of the transcription factor EB-PGC1α axis by beclin-1 controls mitochondrial quality and cardiomyocyte death under stress.

Ma X, Liu H, Murphy JT, Foyil SR, Godar RJ, Abuirqeba H, Weinheimer CJ, Barger PM, Diwan A. Ma X, et al. Among authors: murphy jt. Mol Cell Biol. 2015 Mar;35(6):956-76. doi: 10.1128/MCB.01091-14. Epub 2015 Jan 5. Mol Cell Biol. 2015. PMID: 25561470 Free PMC article.

4

Repetitive stimulation of autophagy-lysosome machinery by intermittent fasting preconditions the myocardium to ischemia-reperfusion injury.

Godar RJ, Ma X, Liu H, Murphy JT, Weinheimer CJ, Kovacs A, Crosby SD, Saftig P, Diwan A. Godar RJ, et al. Among authors: murphy jt. Autophagy. 2015;11(9):1537-60. doi: 10.1080/15548627.2015.1063768. Autophagy. 2015. PMID: 26103523 Free PMC article.

5

IRE1 prevents endoplasmic reticulum membrane permeabilization and cell death under pathological conditions.

Kanekura K, Ma X, Murphy JT, Zhu LJ, Diwan A, Urano F. Kanekura K, et al. Among authors: murphy jt. Sci Signal. 2015 Jun 23;8(382):ra62. doi: 10.1126/scisignal.aaa0341. Sci Signal. 2015. PMID: 26106220 Free PMC article.

6

Transcription Factor EB Activation Rescues Advanced αB-Crystallin Mutation-Induced Cardiomyopathy by Normalizing Desmin Localization.

Ma X, Mani K, Liu H, Kovacs A, Murphy JT, Foroughi L, French BA, Weinheimer CJ, Kraja A, Benjamin IJ, Hill JA, Javaheri A, Diwan A. Ma X, et al. Among authors: murphy jt. J Am Heart Assoc. 2019 Feb 19;8(4):e010866. doi: 10.1161/JAHA.118.010866. J Am Heart Assoc. 2019. PMID: 30773991 Free PMC article.

7

Lifespan Extension in C. elegans Caused by Bacterial Colonization of the Intestine and Subsequent Activation of an Innate Immune Response.

Kumar S, Egan BM, Kocsisova Z, Schneider DL, Murphy JT, Diwan A, Kornfeld K. Kumar S, et al. Dev Cell. 2019 Apr 8;49(1):100-117.e6. doi: 10.1016/j.devcel.2019.03.010. Dev Cell. 2019. PMID: 30965033 Free PMC article.

8

Simple nutrients bypass the requirement for HLH-30 in coupling lysosomal nutrient sensing to survival.

Murphy JT, Liu H, Ma X, Shaver A, Egan BM, Oh C, Boyko A, Mazer T, Ang S, Khopkar R, Javaheri A, Kumar S, Jiang X, Ory D, Mani K, Matkovich SJ, Kornfeld K, Diwan A. Murphy JT, et al. PLoS Biol. 2019 May 14;17(5):e3000245. doi: 10.1371/journal.pbio.3000245. eCollection 2019 May. PLoS Biol. 2019. PMID: 31086360 Free PMC article.

9

TRAF2, an Innate Immune Sensor, Reciprocally Regulates Mitophagy and Inflammation to Maintain Cardiac Myocyte Homeostasis.

Ma X, Rawnsley DR, Kovacs A, Islam M, Murphy JT, Zhao C, Kumari M, Foroughi L, Liu H, Qi K, Diwan A, Hyrc K, Evans S, Satoh T, French BA, Margulies KB, Javaheri A, Razani B, Mann DL, Mani K, Diwan A. Ma X, et al. JACC Basic Transl Sci. 2021 Dec 17;7(3):223-243. doi: 10.1016/j.jacbts.2021.12.002. eCollection 2022 Mar. JACC Basic Transl Sci. 2021. PMID: 35411325 Free PMC article.

10

Phosphorylation of CRYAB Induces a Condensatopathy to Worsen Post-Myocardial Infarction Left Ventricular Remodeling.

Islam M, Rawnsley DR, Ma X, Navid W, Zhao C, Foroughi L, Murphy JT, Navid H, Weinheimer CJ, Kovacs A, Nigro J, Diwan A, Chang R, Kumari M, Young ME, Razani B, Margulies KB, Abdellatif M, Sedej S, Javaheri A, Covey DF, Mani K, Diwan A. Islam M, et al. Among authors: murphy jt. bioRxiv [Preprint]. 2024 Sep 3:2024.08.30.610556. doi: 10.1101/2024.08.30.610556. bioRxiv. 2024. PMID: 39282298 Free PMC article. Preprint.

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