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Gastrin Induces Nuclear Export and Proteasome Degradation of Menin in Enteric Glial Cells.
Sundaresan S, Meininger CA, Kang AJ, Photenhauer AL, Hayes MM, Sahoo N, Grembecka J, Cierpicki T, Ding L, Giordano TJ, Else T, Madrigal DJ, Low MJ, Campbell F, Baker AM, Xu H, Wright NA, Merchant JL. Sundaresan S, et al. Among authors: xu h. Gastroenterology. 2017 Dec;153(6):1555-1567.e15. doi: 10.1053/j.gastro.2017.08.038. Epub 2017 Aug 30. Gastroenterology. 2017. PMID: 28859856 Free PMC article.
Gastric Acid Secretion from Parietal Cells Is Mediated by a Ca2+ Efflux Channel in the Tubulovesicle.
Sahoo N, Gu M, Zhang X, Raval N, Yang J, Bekier M, Calvo R, Patnaik S, Wang W, King G, Samie M, Gao Q, Sahoo S, Sundaresan S, Keeley TM, Wang Y, Marugan J, Ferrer M, Samuelson LC, Merchant JL, Xu H. Sahoo N, et al. Among authors: xu h. Dev Cell. 2017 May 8;41(3):262-273.e6. doi: 10.1016/j.devcel.2017.04.003. Dev Cell. 2017. PMID: 28486130 Free PMC article.
Rapamycin directly activates lysosomal mucolipin TRP channels independent of mTOR.
Zhang X, Chen W, Gao Q, Yang J, Yan X, Zhao H, Su L, Yang M, Gao C, Yao Y, Inoki K, Li D, Shao R, Wang S, Sahoo N, Kudo F, Eguchi T, Ruan B, Xu H. Zhang X, et al. Among authors: xu h. PLoS Biol. 2019 May 21;17(5):e3000252. doi: 10.1371/journal.pbio.3000252. eCollection 2019 May. PLoS Biol. 2019. PMID: 31112550 Free PMC article.
Small-molecule activation of lysosomal TRP channels ameliorates Duchenne muscular dystrophy in mouse models.
Yu L, Zhang X, Yang Y, Li D, Tang K, Zhao Z, He W, Wang C, Sahoo N, Converso-Baran K, Davis CS, Brooks SV, Bigot A, Calvo R, Martinez NJ, Southall N, Hu X, Marugan J, Ferrer M, Xu H. Yu L, et al. Among authors: xu h. Sci Adv. 2020 Feb 7;6(6):eaaz2736. doi: 10.1126/sciadv.aaz2736. eCollection 2020 Feb. Sci Adv. 2020. PMID: 32128386 Free PMC article.
LRRC8 family proteins within lysosomes regulate cellular osmoregulation and enhance cell survival to multiple physiological stresses.
Li P, Hu M, Wang C, Feng X, Zhao Z, Yang Y, Sahoo N, Gu M, Yang Y, Xiao S, Sah R, Cover TL, Chou J, Geha R, Benavides F, Hume RI, Xu H. Li P, et al. Among authors: xu h. Proc Natl Acad Sci U S A. 2020 Nov 17;117(46):29155-29165. doi: 10.1073/pnas.2016539117. Epub 2020 Nov 2. Proc Natl Acad Sci U S A. 2020. PMID: 33139539 Free PMC article.
MCOLN1/TRPML1 finely controls oncogenic autophagy in cancer by mediating zinc influx.
Qi J, Xing Y, Liu Y, Wang MM, Wei X, Sui Z, Ding L, Zhang Y, Lu C, Fei YH, Liu N, Chen R, Wu M, Wang L, Zhong Z, Wang T, Liu Y, Wang Y, Liu J, Xu H, Guo F, Wang W. Qi J, et al. Among authors: xu h. Autophagy. 2021 Dec;17(12):4401-4422. doi: 10.1080/15548627.2021.1917132. Epub 2021 Apr 23. Autophagy. 2021. PMID: 33890549 Free PMC article.
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