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Distinct intracellular sAC-cAMP domains regulate ER Ca2+ signaling and OXPHOS function.
Valsecchi F, Konrad C, D'Aurelio M, Ramos-Espiritu LS, Stepanova A, Burstein SR, Galkin A, Magranè J, Starkov A, Buck J, Levin LR, Manfredi G. Valsecchi F, et al. Among authors: ramos espiritu ls. J Cell Sci. 2017 Nov 1;130(21):3713-3727. doi: 10.1242/jcs.206318. Epub 2017 Sep 1. J Cell Sci. 2017. PMID: 28864766 Free PMC article.
cAMP and mitochondria.
Valsecchi F, Ramos-Espiritu LS, Buck J, Levin LR, Manfredi G. Valsecchi F, et al. Among authors: ramos espiritu ls. Physiology (Bethesda). 2013 May;28(3):199-209. doi: 10.1152/physiol.00004.2013. Physiology (Bethesda). 2013. PMID: 23636265 Free PMC article. Review.
Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase.
Ramos-Espiritu L, Kleinboelting S, Navarrete FA, Alvau A, Visconti PE, Valsecchi F, Starkov A, Manfredi G, Buck H, Adura C, Zippin JH, van den Heuvel J, Glickman JF, Steegborn C, Levin LR, Buck J. Ramos-Espiritu L, et al. Nat Chem Biol. 2016 Oct;12(10):838-44. doi: 10.1038/nchembio.2151. Epub 2016 Aug 22. Nat Chem Biol. 2016. PMID: 27547922 Free PMC article.
The metabolic/pH sensor soluble adenylyl cyclase is a tumor suppressor protein.
Ramos-Espiritu L, Diaz A, Nardin C, Saviola AJ, Shaw F, Plitt T, Yang X, Wolchok J, Pirog EC, Desman G, Sboner A, Zhang T, Xiang J, Merghoub T, Levin LR, Buck J, Zippin JH. Ramos-Espiritu L, et al. Oncotarget. 2016 Jul 19;7(29):45597-45607. doi: 10.18632/oncotarget.10056. Oncotarget. 2016. PMID: 27323809 Free PMC article.
Loss of SATB1 Induces p21-Dependent Cellular Senescence in Post-mitotic Dopaminergic Neurons.
Riessland M, Kolisnyk B, Kim TW, Cheng J, Ni J, Pearson JA, Park EJ, Dam K, Acehan D, Ramos-Espiritu LS, Wang W, Zhang J, Shim JW, Ciceri G, Brichta L, Studer L, Greengard P. Riessland M, et al. Among authors: ramos espiritu ls. Cell Stem Cell. 2019 Oct 3;25(4):514-530.e8. doi: 10.1016/j.stem.2019.08.013. Epub 2019 Sep 19. Cell Stem Cell. 2019. PMID: 31543366 Free PMC article.
13 results