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Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia.
Mettananda S, Fisher CA, Hay D, Badat M, Quek L, Clark K, Hublitz P, Downes D, Kerry J, Gosden M, Telenius J, Sloane-Stanley JA, Faustino P, Coelho A, Doondeea J, Usukhbayar B, Sopp P, Sharpe JA, Hughes JR, Vyas P, Gibbons RJ, Higgs DR. Mettananda S, et al. Among authors: vyas p. Nat Commun. 2017 Sep 4;8(1):424. doi: 10.1038/s41467-017-00479-7. Nat Commun. 2017. PMID: 28871148 Free PMC article.
The alpha-thalassemias.
Higgs DR, Wood WG, Jarman AP, Vickers MA, Wilkie AO, Lamb J, Vyas P, Bennett JP. Higgs DR, et al. Among authors: vyas p. Ann N Y Acad Sci. 1990;612:15-22. doi: 10.1111/j.1749-6632.1990.tb24286.x. Ann N Y Acad Sci. 1990. PMID: 2291543 Review. No abstract available.
Analysis of the human alpha-globin gene cluster in transgenic mice.
Sharpe JA, Wells DJ, Whitelaw E, Vyas P, Higgs DR, Wood WG. Sharpe JA, et al. Among authors: vyas p. Proc Natl Acad Sci U S A. 1993 Dec 1;90(23):11262-6. doi: 10.1073/pnas.90.23.11262. Proc Natl Acad Sci U S A. 1993. PMID: 8248238 Free PMC article.
555 results