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Page 1
A screen for inducers of bHLH activity identifies pitavastatin as a regulator of p21, Rb phosphorylation and E2F target gene expression in pancreatic cancer.
Villarino N, Signaevskaia L, van Niekerk J, Medal R, Kim H, Lahmy R, Scully K, Pinkerton A, Kim S, Lowy A, Itkin-Ansari P. Villarino N, et al. Among authors: pinkerton a. Oncotarget. 2017 Jun 21;8(32):53154-53167. doi: 10.18632/oncotarget.18587. eCollection 2017 Aug 8. Oncotarget. 2017. PMID: 28881801 Free PMC article.
HNF4α antagonists discovered by a high-throughput screen for modulators of the human insulin promoter.
Kiselyuk A, Lee SH, Farber-Katz S, Zhang M, Athavankar S, Cohen T, Pinkerton AB, Ye M, Bushway P, Richardson AD, Hostetler HA, Rodriguez-Lee M, Huang L, Spangler B, Smith L, Higginbotham J, Cashman J, Freeze H, Itkin-Ansari P, Dawson MI, Schroeder F, Cang Y, Mercola M, Levine F. Kiselyuk A, et al. Among authors: pinkerton ab. Chem Biol. 2012 Jul 27;19(7):806-18. doi: 10.1016/j.chembiol.2012.05.014. Chem Biol. 2012. PMID: 22840769 Free PMC article.
Accelerated bottom-up drug design platform enables the discovery of novel stearoyl-CoA desaturase 1 inhibitors for cancer therapy.
von Roemeling CA, Caulfield TR, Marlow L, Bok I, Wen J, Miller JL, Hughes R, Hazlehurst L, Pinkerton AB, Radisky DC, Tun HW, Kim YSB, Lane AL, Copland JA. von Roemeling CA, et al. Among authors: pinkerton ab. Oncotarget. 2017 Oct 6;9(1):3-20. doi: 10.18632/oncotarget.21545. eCollection 2018 Jan 2. Oncotarget. 2017. PMID: 29416592 Free PMC article.
High-throughput screening for small-molecule inhibitors of plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase.
Preuss J, Hedrick M, Sergienko E, Pinkerton A, Mangravita-Novo A, Smith L, Marx C, Fischer E, Jortzik E, Rahlfs S, Becker K, Bode L. Preuss J, et al. Among authors: pinkerton a. J Biomol Screen. 2012 Jul;17(6):738-51. doi: 10.1177/1087057112442382. Epub 2012 Apr 11. J Biomol Screen. 2012. PMID: 22496096 Free PMC article.
Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.
Stanford SM, Aleshin AE, Zhang V, Ardecky RJ, Hedrick MP, Zou J, Ganji SR, Bliss MR, Yamamoto F, Bobkov AA, Kiselar J, Liu Y, Cadwell GW, Khare S, Yu J, Barquilla A, Chung TDY, Mustelin T, Schenk S, Bankston LA, Liddington RC, Pinkerton AB, Bottini N. Stanford SM, et al. Among authors: pinkerton ab. Nat Chem Biol. 2017 Jun;13(6):624-632. doi: 10.1038/nchembio.2344. Epub 2017 Mar 27. Nat Chem Biol. 2017. PMID: 28346406 Free PMC article.
Serine-Threonine Kinase TAO3-Mediated Trafficking of Endosomes Containing the Invadopodia Scaffold TKS5α Promotes Cancer Invasion and Tumor Growth.
Iizuka S, Quintavalle M, Navarro JC, Gribbin KP, Ardecky RJ, Abelman MM, Ma CT, Sergienko E, Zeng FY, Pass I, Thomas GV, McWeeney SK, Hassig CA, Pinkerton AB, Courtneidge SA. Iizuka S, et al. Among authors: pinkerton ab. Cancer Res. 2021 Mar 15;81(6):1472-1485. doi: 10.1158/0008-5472.CAN-20-2383. Epub 2021 Jan 7. Cancer Res. 2021. PMID: 33414172 Free PMC article.
194 results