Isaya G - Search Results

1

Defining the Architecture of the Core Machinery for the Assembly of Fe-S Clusters in Human Mitochondria.

Gakh O, Ranatunga W, Galeano BK, Smith DS 4th, Thompson JR, Isaya G. Gakh O, et al. Among authors: isaya g. Methods Enzymol. 2017;595:107-160. doi: 10.1016/bs.mie.2017.07.003. Epub 2017 Aug 18. Methods Enzymol. 2017. PMID: 28882199

2

Oligomeric yeast frataxin drives assembly of core machinery for mitochondrial iron-sulfur cluster synthesis.

Li H, Gakh O, Smith DY 4th, Isaya G. Li H, et al. Among authors: isaya g. J Biol Chem. 2009 Aug 14;284(33):21971-21980. doi: 10.1074/jbc.M109.011197. Epub 2009 Jun 2. J Biol Chem. 2009. PMID: 19491103 Free PMC article.

3

Architecture of the Yeast Mitochondrial Iron-Sulfur Cluster Assembly Machinery: THE SUB-COMPLEX FORMED BY THE IRON DONOR, Yfh1 PROTEIN, AND THE SCAFFOLD, Isu1 PROTEIN.

Ranatunga W, Gakh O, Galeano BK, Smith DY 4th, Söderberg CA, Al-Karadaghi S, Thompson JR, Isaya G. Ranatunga W, et al. Among authors: isaya g. J Biol Chem. 2016 May 6;291(19):10378-98. doi: 10.1074/jbc.M115.712414. Epub 2016 Mar 3. J Biol Chem. 2016. PMID: 26941001 Free PMC article.

4

Architecture of the Human Mitochondrial Iron-Sulfur Cluster Assembly Machinery.

Gakh O, Ranatunga W, Smith DY 4th, Ahlgren EC, Al-Karadaghi S, Thompson JR, Isaya G. Gakh O, et al. Among authors: isaya g. J Biol Chem. 2016 Sep 30;291(40):21296-21321. doi: 10.1074/jbc.M116.738542. Epub 2016 Aug 12. J Biol Chem. 2016. PMID: 27519411 Free PMC article.

5

Zinc and the iron donor frataxin regulate oligomerization of the scaffold protein to form new Fe-S cluster assembly centers.

Galeano BK, Ranatunga W, Gakh O, Smith DY, Thompson JR, Isaya G. Galeano BK, et al. Among authors: isaya g. Metallomics. 2017 Jun 21;9(6):773-801. doi: 10.1039/c7mt00089h. Metallomics. 2017. PMID: 28548666 Free PMC article.

6

Protein import and processing reconstituted with isolated rat liver mitochondria and recombinant mitochondrial processing peptidase.

Cavadini P, Gakh O, Isaya G. Cavadini P, et al. Among authors: isaya g. Methods. 2002 Apr;26(4):298-306. doi: 10.1016/S1046-2023(02)00035-X. Methods. 2002. PMID: 12054920

7

Supramolecular assemblies of human frataxin are formed via subunit-subunit interactions mediated by a non-conserved amino-terminal region.

O'Neill HA, Gakh O, Isaya G. O'Neill HA, et al. Among authors: isaya g. J Mol Biol. 2005 Jan 21;345(3):433-9. doi: 10.1016/j.jmb.2004.10.074. J Mol Biol. 2005. PMID: 15581888

8

Assembly of human frataxin is a mechanism for detoxifying redox-active iron.

O'Neill HA, Gakh O, Park S, Cui J, Mooney SM, Sampson M, Ferreira GC, Isaya G. O'Neill HA, et al. Among authors: isaya g. Biochemistry. 2005 Jan 18;44(2):537-45. doi: 10.1021/bi048459j. Biochemistry. 2005. PMID: 15641778

9

Assembly of the iron-binding protein frataxin in Saccharomyces cerevisiae responds to dynamic changes in mitochondrial iron influx and stress level.

Gakh O, Smith DY 4th, Isaya G. Gakh O, et al. Among authors: isaya g. J Biol Chem. 2008 Nov 14;283(46):31500-10. doi: 10.1074/jbc.M805415200. Epub 2008 Sep 9. J Biol Chem. 2008. PMID: 18784075 Free PMC article.

10

Normal and Friedreich ataxia cells express different isoforms of frataxin with complementary roles in iron-sulfur cluster assembly.

Gakh O, Bedekovics T, Duncan SF, Smith DY 4th, Berkholz DS, Isaya G. Gakh O, et al. Among authors: isaya g. J Biol Chem. 2010 Dec 3;285(49):38486-501. doi: 10.1074/jbc.M110.145144. Epub 2010 Oct 2. J Biol Chem. 2010. PMID: 20889968 Free PMC article.

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