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Haploid Mammalian Genetic Screen Identifies UBXD8 as a Key Determinant of HMGCR Degradation and Cholesterol Biosynthesis.
Loregger A, Raaben M, Tan J, Scheij S, Moeton M, van den Berg M, Gelberg-Etel H, Stickel E, Roitelman J, Brummelkamp T, Zelcer N. Loregger A, et al. Among authors: scheij s. Arterioscler Thromb Vasc Biol. 2017 Nov;37(11):2064-2074. doi: 10.1161/ATVBAHA.117.310002. Epub 2017 Sep 7. Arterioscler Thromb Vasc Biol. 2017. PMID: 28882874 Free PMC article.
Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism.
Loregger A, Raaben M, Nieuwenhuis J, Tan JME, Jae LT, van den Hengel LG, Hendrix S, van den Berg M, Scheij S, Song JY, Huijbers IJ, Kroese LJ, Ottenhoff R, van Weeghel M, van de Sluis B, Brummelkamp T, Zelcer N. Loregger A, et al. Among authors: scheij s. Nat Commun. 2020 Feb 28;11(1):1128. doi: 10.1038/s41467-020-14811-1. Nat Commun. 2020. PMID: 32111832 Free PMC article.
Inactivation of the E3 Ubiquitin Ligase IDOL Attenuates Diet-Induced Obesity and Metabolic Dysfunction in Mice.
van Loon NM, Ottenhoff R, Kooijman S, Moeton M, Scheij S, Roscam Abbing RLP, Gijbels MJJ, Levels JHM, Sorrentino V, Berbée JFP, Rensen PCN, Zelcer N. van Loon NM, et al. Among authors: scheij s. Arterioscler Thromb Vasc Biol. 2018 Aug;38(8):1785-1795. doi: 10.1161/ATVBAHA.118.311168. Arterioscler Thromb Vasc Biol. 2018. PMID: 29903737 Free PMC article.
Regulation of intestinal LDLR by the LXR-IDOL axis.
van Loon NM, van Wouw SAE, Ottenhoff R, Nelson JK, Kingma J, Scheij S, Moeton M, Zelcer N. van Loon NM, et al. Among authors: scheij s. Atherosclerosis. 2020 Dec;315:1-9. doi: 10.1016/j.atherosclerosis.2020.10.898. Epub 2020 Nov 9. Atherosclerosis. 2020. PMID: 33190106 Free article.
38 results