Mellon PL - Search Results

1

Transcriptional interaction between cFOS and the homeodomain-binding transcription factor VAX1 on the GnRH promoter controls Gnrh1 expression levels in a GnRH neuron maturation specific manner.

Hoffmann HM, Gong P, Tamrazian A, Mellon PL. Hoffmann HM, et al. Among authors: mellon pl. Mol Cell Endocrinol. 2018 Feb 5;461:143-154. doi: 10.1016/j.mce.2017.09.004. Epub 2017 Sep 7. Mol Cell Endocrinol. 2018. PMID: 28890143 Free PMC article.

2

Kisspeptin regulates gonadotropin genes via immediate early gene induction in pituitary gonadotropes.

Witham EA, Meadows JD, Hoffmann HM, Shojaei S, Coss D, Kauffman AS, Mellon PL. Witham EA, et al. Among authors: mellon pl. Mol Endocrinol. 2013 Aug;27(8):1283-94. doi: 10.1210/me.2012-1405. Epub 2013 Jun 14. Mol Endocrinol. 2013. PMID: 23770611 Free PMC article.

3

Heterozygous deletion of ventral anterior homeobox (vax1) causes subfertility in mice.

Hoffmann HM, Tamrazian A, Xie H, Pérez-Millán MI, Kauffman AS, Mellon PL. Hoffmann HM, et al. Among authors: mellon pl. Endocrinology. 2014 Oct;155(10):4043-53. doi: 10.1210/en.2014-1277. Epub 2014 Jul 25. Endocrinology. 2014. PMID: 25060364 Free PMC article.

4

Homeodomain Proteins SIX3 and SIX6 Regulate Gonadotrope-specific Genes During Pituitary Development.

Xie H, Hoffmann HM, Meadows JD, Mayo SL, Trang C, Leming SS, Maruggi C, Davis SW, Larder R, Mellon PL. Xie H, et al. Among authors: mellon pl. Mol Endocrinol. 2015 Jun;29(6):842-55. doi: 10.1210/me.2014-1279. Epub 2015 Apr 27. Mol Endocrinol. 2015. PMID: 25915183 Free PMC article.

5

Deletion of Vax1 from Gonadotropin-Releasing Hormone (GnRH) Neurons Abolishes GnRH Expression and Leads to Hypogonadism and Infertility.

Hoffmann HM, Trang C, Gong P, Kimura I, Pandolfi EC, Mellon PL. Hoffmann HM, et al. Among authors: mellon pl. J Neurosci. 2016 Mar 23;36(12):3506-18. doi: 10.1523/JNEUROSCI.2723-15.2016. J Neurosci. 2016. PMID: 27013679 Free PMC article.

6

The Homeodomain Transcription Factors Vax1 and Six6 Are Required for SCN Development and Function.

Pandolfi EC, Breuer JA, Nguyen Huu VA, Talluri T, Nguyen D, Lee JS, Hu R, Bharti K, Skowronska-Krawczyk D, Gorman MR, Mellon PL, Hoffmann HM. Pandolfi EC, et al. Among authors: mellon pl. Mol Neurobiol. 2020 Feb;57(2):1217-1232. doi: 10.1007/s12035-019-01781-9. Epub 2019 Nov 9. Mol Neurobiol. 2020. PMID: 31705443 Free PMC article.

7

Circadian Rhythms in the Neuronal Network Timing the Luteinizing Hormone Surge.

Tonsfeldt KJ, Mellon PL, Hoffmann HM. Tonsfeldt KJ, et al. Among authors: mellon pl. Endocrinology. 2022 Feb 1;163(2):bqab268. doi: 10.1210/endocr/bqab268. Endocrinology. 2022. PMID: 34967900 Free PMC article. Review.

8

A small population of hypothalamic neurons govern fertility: the critical role of VAX1 in GnRH neuron development and fertility maintenance.

Hoffmann HM, Mellon PL. Hoffmann HM, et al. Among authors: mellon pl. Neurosci Commun (Houst). 2016;2:e1373. Epub 2016 Aug 2. Neurosci Commun (Houst). 2016. PMID: 28164172 Free PMC article.

9

Chromatin status and transcription factor binding to gonadotropin promoters in gonadotrope cell lines.

Xie H, Hoffmann HM, Iyer AK, Brayman MJ, Ngo C, Sunshine MJ, Mellon PL. Xie H, et al. Among authors: mellon pl. Reprod Biol Endocrinol. 2017 Oct 24;15(1):86. doi: 10.1186/s12958-017-0304-z. Reprod Biol Endocrinol. 2017. PMID: 29065928 Free PMC article.

10

Haploinsufficiency of SIX3 Abolishes Male Reproductive Behavior Through Disrupted Olfactory Development, and Impairs Female Fertility Through Disrupted GnRH Neuron Migration.

Pandolfi EC, Hoffmann HM, Schoeller EL, Gorman MR, Mellon PL. Pandolfi EC, et al. Among authors: mellon pl. Mol Neurobiol. 2018 Nov;55(11):8709-8727. doi: 10.1007/s12035-018-1013-0. Epub 2018 Mar 27. Mol Neurobiol. 2018. PMID: 29589282 Free PMC article.

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