Zhang H - Search Results

1

A novel function of CXCL10 in mediating monocyte production of proinflammatory cytokines.

Zhao Q, Kim T, Pang J, Sun W, Yang X, Wang J, Song Y, Zhang H, Sun H, Rangan V, Deshpande S, Tang H, Cvijic ME, Westhouse R, Olah T, Xie J, Struthers M, Salter-Cid L. Zhao Q, et al. Among authors: zhang h. J Leukoc Biol. 2017 Nov;102(5):1271-1280. doi: 10.1189/jlb.5A0717-302. Epub 2017 Sep 12. J Leukoc Biol. 2017. PMID: 28899907

2

Immunoaffinity LC-MS/MS for quantitative determination of a free and total protein target as a target engagement biomarker.

Zhang H, Gu H, Shipkova P, Ciccimaro E, Sun H, Zhao Q, Olah TV. Zhang H, et al. Bioanalysis. 2017 Oct;9(20):1573-1588. doi: 10.4155/bio-2017-0152. Epub 2017 Oct 26. Bioanalysis. 2017. PMID: 29072496 Free article.

3

Quantitation of drug metabolites in the absence of pure metabolite standards by high-performance liquid chromatography coupled with a chemiluminescence nitrogen detector and mass spectrometer.

Deng Y, Wu JT, Zhang H, Olah TV. Deng Y, et al. Among authors: zhang h. Rapid Commun Mass Spectrom. 2004;18(15):1681-5. doi: 10.1002/rcm.1540. Rapid Commun Mass Spectrom. 2004. PMID: 15282765

4

Tandem mass spectrometry with online high-flow reversed-phase extraction and normal-phase chromatography on silica columns with aqueous-organic mobile phase for quantitation of polar compounds in biological fluids.

Deng Y, Zhang H, Wu JT, Olah TV. Deng Y, et al. Among authors: zhang h. Rapid Commun Mass Spectrom. 2005;19(20):2929-34. doi: 10.1002/rcm.2144. Rapid Commun Mass Spectrom. 2005. PMID: 16175657

5

Bioanalytical strategies for developing highly sensitive liquid chromatography/tandem mass spectrometry based methods for the peptide GLP-1 agonists in support of discovery PK/PD studies.

Zhang H, Xin B, Caporuscio C, Olah TV. Zhang H, et al. Rapid Commun Mass Spectrom. 2011 Nov 30;25(22):3427-35. doi: 10.1002/rcm.5241. Rapid Commun Mass Spectrom. 2011. PMID: 22002697

6

Modeling and Simulation of the Pharmacokinetics and Target Engagement of an Antagonist Monoclonal Antibody to Interferon-γ-Induced Protein 10, BMS-986184, in Healthy Participants to Guide Therapeutic Dosing.

Cai W, Leil TA, Gibiansky L, Krishna M, Zhang H, Gu H, Sun H, Throup J, Banerjee S, Girgis I. Cai W, et al. Among authors: zhang h. Clin Pharmacol Drug Dev. 2020 Aug;9(6):689-698. doi: 10.1002/cpdd.784. Epub 2020 Feb 18. Clin Pharmacol Drug Dev. 2020. PMID: 32068354 Free PMC article. Clinical Trial.

7

Development of a highly sensitive liquid chromatography/tandem mass spectrometry method to quantify total and free levels of a target protein, interferon-gamma-inducible protein-10, at picomolar levels in human serum.

Zhang H, Xiao Q, Xin B, Trigona W, Tymiak AA, Dongre AR, Olah TV. Zhang H, et al. Rapid Commun Mass Spectrom. 2014 Jul 15;28(13):1535-43. doi: 10.1002/rcm.6928. Rapid Commun Mass Spectrom. 2014. PMID: 24861605

8

A peptide immunoaffinity LC-MS/MS strategy for quantifying the GPCR protein, S1PR1 in human colon biopsies.

Zhang H, Ciccimaro E, Zalaznick J, Sleczka BG, Menard L, Olah TV, Shipkova P. Zhang H, et al. Bioanalysis. 2020 Sep;12(18):1311-1324. doi: 10.4155/bio-2020-0115. Epub 2020 Sep 18. Bioanalysis. 2020. PMID: 32945691

9

Non-basic azolotriazinone MCHR1 antagonists for the treatment of obesity: An empirical brain-exposures-driven candidate selection for in vivo efficacy studies.

Devasthale P, Wang W, Mignone J, Renduchintala K, Radhakrishnan S, Dhanapal J, Selvaraj J, Kuppusamy R, Pelleymounter MA, Longhi D, Huang N, Flynn N, Azzara AV, Rohrbach K, Devenny J, Rooney S, Thomas M, Glick S, Godonis H, Harvey S, Cullen MJ, Zhang H, Caporuscio C, Stetsko P, Grubb M, Huang C, Zhang L, Freeden C, Murphy BJ, Robl JA, Washburn WN. Devasthale P, et al. Among authors: zhang l, zhang h. Bioorg Med Chem Lett. 2015 Oct 15;25(20):4412-8. doi: 10.1016/j.bmcl.2015.09.018. Epub 2015 Sep 8. Bioorg Med Chem Lett. 2015. PMID: 26386604

10

Identification of a nonbasic melanin hormone receptor 1 antagonist as an antiobesity clinical candidate.

Washburn WN, Manfredi M, Devasthale P, Zhao G, Ahmad S, Hernandez A, Robl JA, Wang W, Mignone J, Wang Z, Ngu K, Pelleymounter MA, Longhi D, Zhao R, Wang B, Huang N, Flynn N, Azzara AV, Barrish JC, Rohrbach K, Devenny JJ, Rooney S, Thomas M, Glick S, Godonis HE, Harvey SJ, Cullen MJ, Zhang H, Caporuscio C, Stetsko P, Grubb M, Maxwell BD, Yang H, Apedo A, Gemzik B, Janovitz EB, Huang C, Zhang L, Freeden C, Murphy BJ. Washburn WN, et al. Among authors: zhang l, zhang h. J Med Chem. 2014 Sep 25;57(18):7509-22. doi: 10.1021/jm500026w. Epub 2014 Sep 9. J Med Chem. 2014. PMID: 25165888

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