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Page 1
Acetyl-4'-phosphopantetheine is stable in serum and prevents phenotypes induced by pantothenate kinase deficiency.
Di Meo I, Colombelli C, Srinivasan B, de Villiers M, Hamada J, Jeong SY, Fox R, Woltjer RL, Tepper PG, Lahaye LL, Rizzetto E, Harrs CH, de Boer T, van der Zwaag M, Jenko B, Čusak A, Pahor J, Kosec G, Grzeschik NA, Hayflick SJ, Tiranti V, Sibon OCM. Di Meo I, et al. Among authors: kosec g. Sci Rep. 2017 Sep 12;7(1):11260. doi: 10.1038/s41598-017-11564-8. Sci Rep. 2017. PMID: 28900161 Free PMC article.
Construction of a new class of tetracycline lead structures with potent antibacterial activity through biosynthetic engineering.
Lešnik U, Lukežič T, Podgoršek A, Horvat J, Polak T, Šala M, Jenko B, Harmrolfs K, Ocampo-Sosa A, Martínez-Martínez L, Herron PR, Fujs Š, Kosec G, Hunter IS, Müller R, Petković H. Lešnik U, et al. Among authors: kosec g. Angew Chem Int Ed Engl. 2015 Mar 23;54(13):3937-40. doi: 10.1002/anie.201411028. Epub 2015 Feb 4. Angew Chem Int Ed Engl. 2015. PMID: 25650563 Free article.
Extracellular 4'-phosphopantetheine is a source for intracellular coenzyme A synthesis.
Srinivasan B, Baratashvili M, van der Zwaag M, Kanon B, Colombelli C, Lambrechts RA, Schaap O, Nollen EA, Podgoršek A, Kosec G, Petković H, Hayflick S, Tiranti V, Reijngoud DJ, Grzeschik NA, Sibon OC. Srinivasan B, et al. Among authors: kosec g. Nat Chem Biol. 2015 Oct;11(10):784-92. doi: 10.1038/nchembio.1906. Epub 2015 Aug 31. Nat Chem Biol. 2015. PMID: 26322826
Lower ototoxicity and absence of hidden hearing loss point to gentamicin C1a and apramycin as promising antibiotics for clinical use.
Ishikawa M, García-Mateo N, Čusak A, López-Hernández I, Fernández-Martínez M, Müller M, Rüttiger L, Singer W, Löwenheim H, Kosec G, Fujs Š, Martínez-Martínez L, Schimmang T, Petković H, Knipper M, Durán-Alonso MB. Ishikawa M, et al. Among authors: kosec g. Sci Rep. 2019 Feb 20;9(1):2410. doi: 10.1038/s41598-019-38634-3. Sci Rep. 2019. PMID: 30787404 Free PMC article.
Origin of the allyl group in FK506 biosynthesis.
Goranovic D, Kosec G, Mrak P, Fujs S, Horvat J, Kuscer E, Kopitar G, Petkovic H. Goranovic D, et al. Among authors: kosec g. J Biol Chem. 2010 May 7;285(19):14292-300. doi: 10.1074/jbc.M109.059600. Epub 2010 Mar 1. J Biol Chem. 2010. PMID: 20194504 Free PMC article.
Annotation of the modular polyketide synthase and nonribosomal peptide synthetase gene clusters in the genome of Streptomyces tsukubaensis NRRL18488.
Blazic M, Starcevic A, Lisfi M, Baranasic D, Goranovic D, Fujs S, Kuscer E, Kosec G, Petkovic H, Cullum J, Hranueli D, Zucko J. Blazic M, et al. Among authors: kosec g. Appl Environ Microbiol. 2012 Dec;78(23):8183-90. doi: 10.1128/AEM.01891-12. Epub 2012 Sep 14. Appl Environ Microbiol. 2012. PMID: 22983969 Free PMC article.
SACE_5599, a putative regulatory protein, is involved in morphological differentiation and erythromycin production in Saccharopolyspora erythraea.
Kirm B, Magdevska V, Tome M, Horvat M, Karničar K, Petek M, Vidmar R, Baebler S, Jamnik P, Fujs Š, Horvat J, Fonovič M, Turk B, Gruden K, Petković H, Kosec G. Kirm B, et al. Among authors: kosec g. Microb Cell Fact. 2013 Dec 17;12:126. doi: 10.1186/1475-2859-12-126. Microb Cell Fact. 2013. PMID: 24341557 Free PMC article.
37 results