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A dual role for the class III PI3K, Vps34, in platelet production and thrombus growth.
Valet C, Levade M, Chicanne G, Bilanges B, Cabou C, Viaud J, Gratacap MP, Gaits-Iacovoni F, Vanhaesebroeck B, Payrastre B, Severin S. Valet C, et al. Among authors: vanhaesebroeck b. Blood. 2017 Nov 2;130(18):2032-2042. doi: 10.1182/blood-2017-04-781641. Epub 2017 Sep 13. Blood. 2017. PMID: 28903944 Free PMC article.
Killing two kinase families with one stone.
Bilanges B, Torbett N, Vanhaesebroeck B. Bilanges B, et al. Among authors: vanhaesebroeck b. Nat Chem Biol. 2008 Nov;4(11):648-9. doi: 10.1038/nchembio1108-648. Nat Chem Biol. 2008. PMID: 18936744 No abstract available.
Deletion of the p110beta isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo.
Martin V, Guillermet-Guibert J, Chicanne G, Cabou C, Jandrot-Perrus M, Plantavid M, Vanhaesebroeck B, Payrastre B, Gratacap MP. Martin V, et al. Among authors: vanhaesebroeck b. Blood. 2010 Mar 11;115(10):2008-13. doi: 10.1182/blood-2009-04-217224. Epub 2010 Jan 11. Blood. 2010. PMID: 20065293 Free article.
The emerging mechanisms of isoform-specific PI3K signalling.
Vanhaesebroeck B, Guillermet-Guibert J, Graupera M, Bilanges B. Vanhaesebroeck B, et al. Nat Rev Mol Cell Biol. 2010 May;11(5):329-41. doi: 10.1038/nrm2882. Epub 2010 Apr 9. Nat Rev Mol Cell Biol. 2010. PMID: 20379207 Review.
A new tool to dissect the function of p70 S6 kinase.
Bilanges B, Vanhaesebroeck B. Bilanges B, et al. Among authors: vanhaesebroeck b. Biochem J. 2010 Oct 15;431(2):e1-3. doi: 10.1042/BJ20101445. Biochem J. 2010. PMID: 20874709
Long-term p110α PI3K inactivation exerts a beneficial effect on metabolism.
Foukas LC, Bilanges B, Bettedi L, Pearce W, Ali K, Sancho S, Withers DJ, Vanhaesebroeck B. Foukas LC, et al. Among authors: vanhaesebroeck b. EMBO Mol Med. 2013 Apr;5(4):563-71. doi: 10.1002/emmm.201201953. Epub 2013 Mar 11. EMBO Mol Med. 2013. PMID: 23483710 Free PMC article.
222 results