Darcy PK - Search Results

1

Agonist immunotherapy restores T cell function following MEK inhibition improving efficacy in breast cancer.

Dushyanthen S, Teo ZL, Caramia F, Savas P, Mintoff CP, Virassamy B, Henderson MA, Luen SJ, Mansour M, Kershaw MH, Trapani JA, Neeson PJ, Salgado R, McArthur GA, Balko JM, Beavis PA, Darcy PK, Loi S. Dushyanthen S, et al. Among authors: darcy pk. Nat Commun. 2017 Sep 19;8(1):606. doi: 10.1038/s41467-017-00728-9. Nat Commun. 2017. PMID: 28928458 Free PMC article.

2

Redirected cytotoxic effector function. Requirements for expression of chimeric single chain high affinity immunoglobulin e receptors.

Kershaw MH, Darcy PK, Hulett MD, Hogarth PM, Trapani JA, Smyth MJ. Kershaw MH, et al. Among authors: darcy pk. J Biol Chem. 1996 Aug 30;271(35):21214-20. doi: 10.1074/jbc.271.35.21214. J Biol Chem. 1996. PMID: 8702893 Free article.

3

The use of chimeric human Fc(epsilon) receptor I to redirect cytotoxic T lymphocytes to tumors.

Kershaw MH, Darcy PK, Trapani JA, Smyth MJ. Kershaw MH, et al. Among authors: darcy pk. J Leukoc Biol. 1996 Dec;60(6):721-8. doi: 10.1002/jlb.60.6.721. J Leukoc Biol. 1996. PMID: 8975874

4

Adoptive transfer: the role of perforin in mouse cytotoxic T lymphocyte rejection of human tumor xenografts in vivo.

Smyth MJ, Kershaw MH, Darcy PK, Trapani JA. Smyth MJ, et al. Among authors: darcy pk. Xenotransplantation. 1998 May;5(2):146-53. doi: 10.1111/j.1399-3089.1998.tb00020.x. Xenotransplantation. 1998. PMID: 9584828

5

Xenospecific CD8+ cytotoxic T lymphocyte generation: accessory function for CD4+ T cells and natural killer 1.1+ cells.

Smyth MJ, Kershaw MH, Darcy PK. Smyth MJ, et al. Among authors: darcy pk. Transplantation. 1998 May 15;65(9):1278-81. doi: 10.1097/00007890-199805150-00025. Transplantation. 1998. PMID: 9603183

6

Expression in cytotoxic T lymphocytes of a single-chain anti-carcinoembryonic antigen antibody. Redirected Fas ligand-mediated lysis of colon carcinoma.

Darcy PK, Kershaw MH, Trapani JA, Smyth MJ. Darcy PK, et al. Eur J Immunol. 1998 May;28(5):1663-72. doi: 10.1002/(SICI)1521-4141(199805)28:05<1663::AID-IMMU1663>3.0.CO;2-L. Eur J Immunol. 1998. PMID: 9603473 Free article.

7

Tumor-specific IgE-mediated inhibition of human colorectal carcinoma xenograft growth.

Kershaw MH, Darcy PK, Trapani JA, MacGregor D, Smyth MJ. Kershaw MH, et al. Among authors: darcy pk. Oncol Res. 1998;10(3):133-42. Oncol Res. 1998. PMID: 9700724

8

Fas-ligand-mediated lysis of erbB-2-expressing tumour cells by redirected cytotoxic T lymphocytes.

Haynes NM, Smyth MJ, Kershaw MH, Trapani JA, Darcy PK. Haynes NM, et al. Among authors: darcy pk. Cancer Immunol Immunother. 1999 Jan;47(5):278-86. doi: 10.1007/s002620050532. Cancer Immunol Immunother. 1999. PMID: 10022472 Free PMC article.

9

Redirected perforin-dependent lysis of colon carcinoma by ex vivo genetically engineered CTL.

Darcy PK, Haynes NM, Snook MB, Trapani JA, Cerruti L, Jane SM, Smyth MJ. Darcy PK, et al. J Immunol. 2000 Apr 1;164(7):3705-12. doi: 10.4049/jimmunol.164.7.3705. J Immunol. 2000. PMID: 10725729

10

Redirecting mouse CTL against colon carcinoma: superior signaling efficacy of single-chain variable domain chimeras containing TCR-zeta vs Fc epsilon RI-gamma.

Haynes NM, Snook MB, Trapani JA, Cerruti L, Jane SM, Smyth MJ, Darcy PK. Haynes NM, et al. Among authors: darcy pk. J Immunol. 2001 Jan 1;166(1):182-7. doi: 10.4049/jimmunol.166.1.182. J Immunol. 2001. PMID: 11123291

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