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Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy number.
Lyons JJ, Yu X, Hughes JD, Le QT, Jamil A, Bai Y, Ho N, Zhao M, Liu Y, O'Connell MP, Trivedi NN, Nelson C, DiMaggio T, Jones N, Matthews H, Lewis KL, Oler AJ, Carlson RJ, Arkwright PD, Hong C, Agama S, Wilson TM, Tucker S, Zhang Y, McElwee JJ, Pao M, Glover SC, Rothenberg ME, Hohman RJ, Stone KD, Caughey GH, Heller T, Metcalfe DD, Biesecker LG, Schwartz LB, Milner JD. Lyons JJ, et al. Among authors: liu y. Nat Genet. 2016 Dec;48(12):1564-1569. doi: 10.1038/ng.3696. Epub 2016 Oct 17. Nat Genet. 2016. PMID: 27749843 Free PMC article.
GATA-2-deficient mast cells limit IgE-mediated immediate hypersensitivity reactions in human subjects.
Desai A, Sowerwine K, Liu Y, Lawrence MG, Chovanec J, Hsu AP, O'Connell MP, Kim J, Boris L, Jones N, Wisch L, Eisch RR, Carter MC, Komarow HD, Zerbe C, Milner JD, Maric I, Sun X, Lee CR, Tunc I, Pirooznia M, Stone KD, Holland SM, Metcalfe DD, Lyons JJ. Desai A, et al. Among authors: liu y. J Allergy Clin Immunol. 2019 Aug;144(2):613-617.e14. doi: 10.1016/j.jaci.2019.05.007. Epub 2019 May 15. J Allergy Clin Immunol. 2019. PMID: 31102699 No abstract available.
Heritable risk for severe anaphylaxis associated with increased α-tryptase-encoding germline copy number at TPSAB1.
Lyons JJ, Chovanec J, O'Connell MP, Liu Y, Šelb J, Zanotti R, Bai Y, Kim J, Le QT, DiMaggio T, Schwartz LB, Komarow HD, Rijavec M, Carter MC, Milner JD, Bonadonna P, Metcalfe DD, Korošec P. Lyons JJ, et al. Among authors: liu y. J Allergy Clin Immunol. 2021 Feb;147(2):622-632. doi: 10.1016/j.jaci.2020.06.035. Epub 2020 Jul 24. J Allergy Clin Immunol. 2021. PMID: 32717252
Routine KIT p.D816V screening identifies clonal mast cell disease in patients with Hymenoptera allergy regularly missed using baseline tryptase levels alone.
Šelb J, Rijavec M, Eržen R, Zidarn M, Kopač P, Škerget M, Bajrović N, Luzar AD, Park YH, Liu Y, Šerbec VČ, Zver S, Košnik M, Lyons JJ, Korošec P. Šelb J, et al. Among authors: liu y. J Allergy Clin Immunol. 2021 Aug;148(2):621-626.e7. doi: 10.1016/j.jaci.2021.02.043. Epub 2021 Mar 19. J Allergy Clin Immunol. 2021. PMID: 33753098 Free PMC article.
Genetically defined individual reference ranges for tryptase limit unnecessary procedures and unmask myeloid neoplasms.
Chovanec J, Tunc I, Hughes J, Halstead J, Mateja A, Liu Y, O'Connell MP, Kim J, Park YH, Wang Q, Le Q, Pirooznia M, Trivedi NN, Bai Y, Yin Y, Hsu AP, McElwee J, Lassiter S, Nelson C, Bandoh J, DiMaggio T, Šelb J, Rijavec M, Carter MC, Komarow HD, Sabato V, Steinberg J, Hafer KM, Feuille E, Hourigan CS, Lack J, Khoury P, Maric I, Zanotti R, Bonadonna P, Schwartz LB, Milner JD, Glover SC, Ebo DG, Korošec P, Caughey GH, Brittain EH, Busby B, Metcalfe DD, Lyons JJ. Chovanec J, et al. Among authors: liu y. Blood Adv. 2023 May 9;7(9):1796-1810. doi: 10.1182/bloodadvances.2022007936. Blood Adv. 2023. PMID: 36170795 Free PMC article.
Severe food allergy reactions are associated with α-tryptase.
Lang A, Kubala S, Grieco MC, Mateja A, Pongracic J, Liu Y, Frischmeyer-Guerrerio PA, Kumar R, Lyons JJ. Lang A, et al. Among authors: liu y. J Allergy Clin Immunol. 2023 Oct;152(4):933-939. doi: 10.1016/j.jaci.2023.07.014. Epub 2023 Aug 7. J Allergy Clin Immunol. 2023. PMID: 37558059 Free PMC article.
Underlying systemic mastocytosis in patients with unexplained osteoporosis: score proposal.
Tanasi I, Crosera L, Taus F, Orsolini G, Adami G, Olivieri F, Bernardelli A, Bonadonna P, Nalin F, Sella S, Giannini S, Liu Y, Mannelli F, Vanderwert F, Bonifacio M, Krampera M, Rossini M, Lyons JJ, Zanotti R. Tanasi I, et al. Among authors: liu y. Bone. 2024 Sep;186:117141. doi: 10.1016/j.bone.2024.117141. Epub 2024 May 31. Bone. 2024. PMID: 38823568
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