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Enantioselective Total Synthesis of Antibiotic CJ-16,264, Synthesis and Biological Evaluation of Designed Analogues, and Discovery of Highly Potent and Simpler Antibacterial Agents.
Nicolaou KC, Pulukuri KK, Rigol S, Buchman M, Shah AA, Cen N, McCurry MD, Beabout K, Shamoo Y. Nicolaou KC, et al. Among authors: pulukuri kk. J Am Chem Soc. 2017 Nov 8;139(44):15868-15877. doi: 10.1021/jacs.7b08749. Epub 2017 Oct 24. J Am Chem Soc. 2017. PMID: 29064688 Free PMC article.
Streamlined Total Synthesis of Trioxacarcins and Its Application to the Design, Synthesis, and Biological Evaluation of Analogues Thereof. Discovery of Simpler Designed and Potent Trioxacarcin Analogues.
Nicolaou KC, Chen P, Zhu S, Cai Q, Erande RD, Li R, Sun H, Pulukuri KK, Rigol S, Aujay M, Sandoval J, Gavrilyuk J. Nicolaou KC, et al. Among authors: pulukuri kk. J Am Chem Soc. 2017 Nov 1;139(43):15467-15478. doi: 10.1021/jacs.7b08820. Epub 2017 Oct 20. J Am Chem Soc. 2017. PMID: 29052423
Design, Synthesis, and Biological Evaluation of Tubulysin Analogues, Linker-Drugs, and Antibody-Drug Conjugates, Insights into Structure-Activity Relationships, and Tubulysin-Tubulin Binding Derived from X-ray Crystallographic Analysis.
Nicolaou KC, Pan S, Pulukuri KK, Ye Q, Rigol S, Erande RD, Vourloumis D, Nocek BP, Munneke S, Lyssikatos J, Valdiosera A, Gu C, Lin B, Sarvaiaya H, Trinidad J, Sandoval J, Lee C, Hammond M, Aujay M, Taylor N, Pysz M, Purcell JW, Gavrilyuk J. Nicolaou KC, et al. Among authors: pulukuri kk. J Org Chem. 2021 Feb 19;86(4):3377-3421. doi: 10.1021/acs.joc.0c02755. Epub 2021 Feb 5. J Org Chem. 2021. PMID: 33544599
16 results