Champeil E - Search Results

1

Acetone promoted 1,4-migration of an alkoxycarbonyl group on a syn-1,2-diamine.

Napolitano T, Cheng SY, Nielsen B, Choi C, Aguilar W, Paz MM, Sapse AM, Champeil E. Napolitano T, et al. Among authors: champeil e. Tetrahedron Lett. 2017 Feb 15;58(7):597-601. doi: 10.1016/j.tetlet.2016.12.047. Epub 2017 Jan 3. Tetrahedron Lett. 2017. PMID: 28943668 Free PMC article.

2

Synthesis of an oligodeoxyribonucleotide adduct of mitomycin C by the postoligomerization method via a triamino mitosene.

Champeil E, Paz MM, Ladwa S, Clement CC, Zatorski A, Tomasz M. Champeil E, et al. J Am Chem Soc. 2008 Jul 23;130(29):9556-65. doi: 10.1021/ja802118p. Epub 2008 Jun 28. J Am Chem Soc. 2008. PMID: 18588303 Free PMC article.

3

Mapping DNA adducts of mitomycin C and decarbamoyl mitomycin C in cell lines using liquid chromatography/ electrospray tandem mass spectrometry.

Paz MM, Ladwa S, Champeil E, Liu Y, Rockwell S, Boamah EK, Bargonetti J, Callahan J, Roach J, Tomasz M. Paz MM, et al. Among authors: champeil e. Chem Res Toxicol. 2008 Dec;21(12):2370-8. doi: 10.1021/tx8002615. Chem Res Toxicol. 2008. PMID: 19053323 Free PMC article.

4

Synthesis of a major mitomycin C DNA adduct via a triaminomitosene.

Champeil E, Paz MM, Lukasiewicz E, Kong WS, Watson S, Sapse AM. Champeil E, et al. Bioorg Med Chem Lett. 2012 Dec 1;22(23):7198-200. doi: 10.1016/j.bmcl.2012.09.052. Epub 2012 Sep 25. Bioorg Med Chem Lett. 2012. PMID: 23079525

5

Synthesis of Mitomycin C and Decarbamoylmitomycin C N(2) deoxyguanosine-adducts.

Champeil E, Cheng SY, Huang BT, Conchero-Guisan M, Martinez T, Paz MM, Sapse AM. Champeil E, et al. Bioorg Chem. 2016 Apr;65:90-9. doi: 10.1016/j.bioorg.2016.02.003. Epub 2016 Feb 11. Bioorg Chem. 2016. PMID: 26894558 Free PMC article.

6

Mitomycin C and decarbamoyl mitomycin C induce p53-independent p21WAF1/CIP1 activation.

Cheng SY, Seo J, Huang BT, Napolitano T, Champeil E. Cheng SY, et al. Among authors: champeil e. Int J Oncol. 2016 Nov;49(5):1815-1824. doi: 10.3892/ijo.2016.3703. Epub 2016 Sep 23. Int J Oncol. 2016. PMID: 27666201 Free PMC article.

7

Sequence-Dependent Diastereospecific and Diastereodivergent Crosslinking of DNA by Decarbamoylmitomycin C.

Aguilar W, Paz MM, Vargas A, Clement CC, Cheng SY, Champeil E. Aguilar W, et al. Among authors: champeil e. Chemistry. 2018 Apr 20;24(23):6030-6035. doi: 10.1002/chem.201705771. Epub 2018 Mar 27. Chemistry. 2018. PMID: 29504661 Free PMC article.

8

Interdependent Sequence Selectivity and Diastereoselectivity in the Alkylation of DNA by Decarbamoylmitomycin C.

Aguilar W, Paz MM, Vargas A, Zheng M, Cheng SY, Champeil E. Aguilar W, et al. Among authors: champeil e. Chemistry. 2018 Sep 6;24(50):13278-13289. doi: 10.1002/chem.201802038. Epub 2018 Aug 10. Chemistry. 2018. PMID: 29958326 Free PMC article.

9

Isolation and Rationale for the Formation of Isomeric Decarbamoylmitomycin C- N⁶-deoxyadenosine Adducts in DNA.

Zacarias O, Aguilar W, Paz MM, Tsukanov S, Zheng M, Cheng SY, Pradhan P, Champeil E. Zacarias O, et al. Among authors: champeil e. Chem Res Toxicol. 2018 Aug 20;31(8):762-771. doi: 10.1021/acs.chemrestox.8b00102. Epub 2018 Aug 2. Chem Res Toxicol. 2018. PMID: 30035537 Free PMC article.

10

Involvement of Akt in mitomycin C and its analog triggered cytotoxicity in MCF-7 and K562 cancer cells.

Cheng SY, Vargas A, Lee JY, Clement CC, Champeil E. Cheng SY, et al. Among authors: champeil e. Chem Biol Drug Des. 2018 Dec;92(6):2022-2034. doi: 10.1111/cbdd.13374. Epub 2018 Sep 11. Chem Biol Drug Des. 2018. PMID: 30091208 Free PMC article.

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