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The BET/BRD inhibitor JQ1 improves brain plasticity in WT and APP mice.
Benito E, Ramachandran B, Schroeder H, Schmidt G, Urbanke H, Burkhardt S, Capece V, Dean C, Fischer A. Benito E, et al. Among authors: fischer a. Transl Psychiatry. 2017 Sep 26;7(9):e1239. doi: 10.1038/tp.2017.202. Transl Psychiatry. 2017. PMID: 28949335 Free PMC article.
Altered histone acetylation is associated with age-dependent memory impairment in mice.
Peleg S, Sananbenesi F, Zovoilis A, Burkhardt S, Bahari-Javan S, Agis-Balboa RC, Cota P, Wittnam JL, Gogol-Doering A, Opitz L, Salinas-Riester G, Dettenhofer M, Kang H, Farinelli L, Chen W, Fischer A. Peleg S, et al. Among authors: fischer a. Science. 2010 May 7;328(5979):753-6. doi: 10.1126/science.1186088. Science. 2010. PMID: 20448184
A hippocampal insulin-growth factor 2 pathway regulates the extinction of fear memories.
Agis-Balboa RC, Arcos-Diaz D, Wittnam J, Govindarajan N, Blom K, Burkhardt S, Haladyniak U, Agbemenyah HY, Zovoilis A, Salinas-Riester G, Opitz L, Sananbenesi F, Fischer A. Agis-Balboa RC, et al. Among authors: fischer a. EMBO J. 2011 Aug 26;30(19):4071-83. doi: 10.1038/emboj.2011.293. EMBO J. 2011. PMID: 21873981 Free PMC article.
microRNA-34c is a novel target to treat dementias.
Zovoilis A, Agbemenyah HY, Agis-Balboa RC, Stilling RM, Edbauer D, Rao P, Farinelli L, Delalle I, Schmitt A, Falkai P, Bahari-Javan S, Burkhardt S, Sananbenesi F, Fischer A. Zovoilis A, et al. Among authors: fischer a. EMBO J. 2011 Sep 23;30(20):4299-308. doi: 10.1038/emboj.2011.327. EMBO J. 2011. PMID: 21946562 Free PMC article.
HDAC1 regulates fear extinction in mice.
Bahari-Javan S, Maddalena A, Kerimoglu C, Wittnam J, Held T, Bähr M, Burkhardt S, Delalle I, Kügler S, Fischer A, Sananbenesi F. Bahari-Javan S, et al. Among authors: fischer a. J Neurosci. 2012 Apr 11;32(15):5062-73. doi: 10.1523/JNEUROSCI.0079-12.2012. J Neurosci. 2012. PMID: 22496552 Free PMC article.
Histone-methyltransferase MLL2 (KMT2B) is required for memory formation in mice.
Kerimoglu C, Agis-Balboa RC, Kranz A, Stilling R, Bahari-Javan S, Benito-Garagorri E, Halder R, Burkhardt S, Stewart AF, Fischer A. Kerimoglu C, et al. Among authors: fischer a. J Neurosci. 2013 Feb 20;33(8):3452-64. doi: 10.1523/JNEUROSCI.3356-12.2013. J Neurosci. 2013. PMID: 23426673 Free PMC article.
5,287 results