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Parallel Accumulation of Tumor Hyaluronan, Collagen, and Other Drivers of Tumor Progression.
Li X, Shepard HM, Cowell JA, Zhao C, Osgood RJ, Rosengren S, Blouw B, Garrovillo SA, Pagel MD, Whatcott CJ, Han H, Von Hoff DD, Taverna DM, LaBarre MJ, Maneval DC, Thompson CB. Li X, et al. Among authors: maneval dc. Clin Cancer Res. 2018 Oct 1;24(19):4798-4807. doi: 10.1158/1078-0432.CCR-17-3284. Epub 2018 Jul 3. Clin Cancer Res. 2018. PMID: 30084839 Free PMC article.
A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Recombinant Human Hyaluronidase PH20 Administered Intravenously in Healthy Volunteers.
Printz MA, Dychter SS, DeNoia EP, Harrigan R, Sugarman BJ, Zepeda M, Souratha J, Kang DW, Maneval DC. Printz MA, et al. Among authors: maneval dc. Curr Ther Res Clin Exp. 2020 Aug 19;93:100604. doi: 10.1016/j.curtheres.2020.100604. eCollection 2020. Curr Ther Res Clin Exp. 2020. PMID: 32963641 Free PMC article.
PH20 is not expressed in murine CNS and oligodendrocyte precursor cells.
Marella M, Ouyang J, Zombeck J, Zhao C, Huang L, Connor RJ, Phan KB, Jorge MC, Printz MA, Paladini RD, Gelb AB, Huang Z, Frost GI, Sugarman BJ, Steinman L, Wei G, Shepard HM, Maneval DC, Lapinskas PJ. Marella M, et al. Among authors: maneval dc. Ann Clin Transl Neurol. 2017 Feb 23;4(3):191-211. doi: 10.1002/acn3.393. eCollection 2017 Mar. Ann Clin Transl Neurol. 2017. PMID: 28275653 Free PMC article.
The growth of a xenograft breast cancer tumor model with engineered hyaluronan-accumulating stroma is dependent on hyaluronan and independent of CD44.
Zhao C, Thompson BJ, Chen K, Gao F, Blouw B, Marella M, Zimmerman S, Kimbler T, Garrovillo S, Bahn J, Huang L, Huang Z, Shepard HM, Rosengren S, Thanos CD, Maneval DC. Zhao C, et al. Among authors: maneval dc. Oncotarget. 2019 Nov 12;10(61):6561-6576. doi: 10.18632/oncotarget.27302. eCollection 2019 Nov 12. Oncotarget. 2019. PMID: 31762938 Free PMC article.
Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer.
Jacobetz MA, Chan DS, Neesse A, Bapiro TE, Cook N, Frese KK, Feig C, Nakagawa T, Caldwell ME, Zecchini HI, Lolkema MP, Jiang P, Kultti A, Thompson CB, Maneval DC, Jodrell DI, Frost GI, Shepard HM, Skepper JN, Tuveson DA. Jacobetz MA, et al. Among authors: maneval dc. Gut. 2013 Jan;62(1):112-20. doi: 10.1136/gutjnl-2012-302529. Epub 2012 Mar 30. Gut. 2013. PMID: 22466618 Free PMC article.
73 results