Saretzki G - Search Results

1

Human iPSC disease modelling reveals functional and structural defects in retinal pigment epithelial cells harbouring the m.3243A > G mitochondrial DNA mutation.

Chichagova V, Hallam D, Collin J, Buskin A, Saretzki G, Armstrong L, Yu-Wai-Man P, Lako M, Steel DH. Chichagova V, et al. Among authors: saretzki g. Sci Rep. 2017 Sep 26;7(1):12320. doi: 10.1038/s41598-017-12396-2. Sci Rep. 2017. PMID: 28951556 Free PMC article.

2

A role for nucleoprotein Zap3 in the reduction of telomerase activity during embryonic stem cell differentiation.

Armstrong L, Lako M, van Herpe I, Evans J, Saretzki G, Hole N. Armstrong L, et al. Among authors: saretzki g. Mech Dev. 2004 Dec;121(12):1509-22. doi: 10.1016/j.mod.2004.07.005. Mech Dev. 2004. PMID: 15511642 Free article.

3

Stress defense in murine embryonic stem cells is superior to that of various differentiated murine cells.

Saretzki G, Armstrong L, Leake A, Lako M, von Zglinicki T. Saretzki G, et al. Stem Cells. 2004;22(6):962-71. doi: 10.1634/stemcells.22-6-962. Stem Cells. 2004. PMID: 15536187

4

Overexpression of telomerase confers growth advantage, stress resistance, and enhanced differentiation of ESCs toward the hematopoietic lineage.

Armstrong L, Saretzki G, Peters H, Wappler I, Evans J, Hole N, von Zglinicki T, Lako M. Armstrong L, et al. Among authors: saretzki g. Stem Cells. 2005 Apr;23(4):516-29. doi: 10.1634/stemcells.2004-0269. Stem Cells. 2005. PMID: 15790773

5

Downregulation of multiple stress defense mechanisms during differentiation of human embryonic stem cells.

Saretzki G, Walter T, Atkinson S, Passos JF, Bareth B, Keith WN, Stewart R, Hoare S, Stojkovic M, Armstrong L, von Zglinicki T, Lako M. Saretzki G, et al. Stem Cells. 2008 Feb;26(2):455-64. doi: 10.1634/stemcells.2007-0628. Epub 2007 Nov 29. Stem Cells. 2008. PMID: 18055443

6

A key role for telomerase reverse transcriptase unit in modulating human embryonic stem cell proliferation, cell cycle dynamics, and in vitro differentiation.

Yang C, Przyborski S, Cooke MJ, Zhang X, Stewart R, Anyfantis G, Atkinson SP, Saretzki G, Armstrong L, Lako M. Yang C, et al. Among authors: saretzki g. Stem Cells. 2008 Apr;26(4):850-63. doi: 10.1634/stemcells.2007-0677. Epub 2008 Jan 17. Stem Cells. 2008. PMID: 18203676

7

Human induced pluripotent stem cell lines show stress defense mechanisms and mitochondrial regulation similar to those of human embryonic stem cells.

Armstrong L, Tilgner K, Saretzki G, Atkinson SP, Stojkovic M, Moreno R, Przyborski S, Lako M. Armstrong L, et al. Among authors: saretzki g. Stem Cells. 2010 Apr;28(4):661-73. doi: 10.1002/stem.307. Stem Cells. 2010. PMID: 20073085

8

Derivation and functional analysis of patient-specific induced pluripotent stem cells as an in vitro model of chronic granulomatous disease.

Jiang Y, Cowley SA, Siler U, Melguizo D, Tilgner K, Browne C, Dewilton A, Przyborski S, Saretzki G, James WS, Seger RA, Reichenbach J, Lako M, Armstrong L. Jiang Y, et al. Among authors: saretzki g. Stem Cells. 2012 Apr;30(4):599-611. doi: 10.1002/stem.1053. Stem Cells. 2012. PMID: 22311747 Free PMC article.

9

Brief report: human pluripotent stem cell models of fanconi anemia deficiency reveal an important role for fanconi anemia proteins in cellular reprogramming and survival of hematopoietic progenitors.

Yung SK, Tilgner K, Ledran MH, Habibollah S, Neganova I, Singhapol C, Saretzki G, Stojkovic M, Armstrong L, Przyborski S, Lako M. Yung SK, et al. Among authors: saretzki g. Stem Cells. 2013 May;31(5):1022-9. doi: 10.1002/stem.1308. Stem Cells. 2013. PMID: 23280624

10

A human iPSC model of Ligase IV deficiency reveals an important role for NHEJ-mediated-DSB repair in the survival and genomic stability of induced pluripotent stem cells and emerging haematopoietic progenitors.

Tilgner K, Neganova I, Moreno-Gimeno I, Al-Aama JY, Burks D, Yung S, Singhapol C, Saretzki G, Evans J, Gorbunova V, Gennery A, Przyborski S, Stojkovic M, Armstrong L, Jeggo P, Lako M. Tilgner K, et al. Among authors: saretzki g. Cell Death Differ. 2013 Aug;20(8):1089-100. doi: 10.1038/cdd.2013.44. Epub 2013 May 31. Cell Death Differ. 2013. PMID: 23722522 Free PMC article.

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