Marmorstein R - Search Results

1

Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.

Lasko LM, Jakob CG, Edalji RP, Qiu W, Montgomery D, Digiammarino EL, Hansen TM, Risi RM, Frey R, Manaves V, Shaw B, Algire M, Hessler P, Lam LT, Uziel T, Faivre E, Ferguson D, Buchanan FG, Martin RL, Torrent M, Chiang GG, Karukurichi K, Langston JW, Weinert BT, Choudhary C, de Vries P, Van Drie JH, McElligott D, Kesicki E, Marmorstein R, Sun C, Cole PA, Rosenberg SH, Michaelides MR, Lai A, Bromberg KD. Lasko LM, et al. Among authors: marmorstein r. Nature. 2017 Oct 5;550(7674):128-132. doi: 10.1038/nature24028. Epub 2017 Sep 27. Nature. 2017. PMID: 28953875 Free PMC article.

2

Crystal structure of trp repressor/operator complex at atomic resolution.

Otwinowski Z, Schevitz RW, Zhang RG, Lawson CL, Joachimiak A, Marmorstein RQ, Luisi BF, Sigler PB. Otwinowski Z, et al. Among authors: marmorstein rq. Nature. 1988 Sep 22;335(6188):321-9. doi: 10.1038/335321a0. Nature. 1988. PMID: 3419502

3

Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide.

Rojas JR, Trievel RC, Zhou J, Mo Y, Li X, Berger SL, Allis CD, Marmorstein R. Rojas JR, et al. Among authors: marmorstein r. Nature. 1999 Sep 2;401(6748):93-8. doi: 10.1038/43487. Nature. 1999. PMID: 10485713

4

Application of a fluorescent histone acetyltransferase assay to probe the substrate specificity of the human p300/CBP-associated factor.

Trievel RC, Li FY, Marmorstein R. Trievel RC, et al. Among authors: marmorstein r. Anal Biochem. 2000 Dec 15;287(2):319-28. doi: 10.1006/abio.2000.4855. Anal Biochem. 2000. PMID: 11112280 Free article.

5

Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor.

Poux AN, Cebrat M, Kim CM, Cole PA, Marmorstein R. Poux AN, et al. Among authors: marmorstein r. Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14065-70. doi: 10.1073/pnas.222373899. Epub 2002 Oct 21. Proc Natl Acad Sci U S A. 2002. PMID: 12391296 Free PMC article.

6

A mechanism-based inactivator for histone demethylase LSD1.

Culhane JC, Szewczuk LM, Liu X, Da G, Marmorstein R, Cole PA. Culhane JC, et al. Among authors: marmorstein r. J Am Chem Soc. 2006 Apr 12;128(14):4536-7. doi: 10.1021/ja0602748. J Am Chem Soc. 2006. PMID: 16594666

7

Multiple roles for acetylation in the interaction of p300 HAT with ATF-2.

Karanam B, Wang L, Wang D, Liu X, Marmorstein R, Cotter R, Cole PA. Karanam B, et al. Among authors: marmorstein r. Biochemistry. 2007 Jul 17;46(28):8207-16. doi: 10.1021/bi7000054. Epub 2007 Jun 23. Biochemistry. 2007. PMID: 17590016 Free PMC article.

8

The structural basis of protein acetylation by the p300/CBP transcriptional coactivator.

Liu X, Wang L, Zhao K, Thompson PR, Hwang Y, Marmorstein R, Cole PA. Liu X, et al. Among authors: marmorstein r. Nature. 2008 Feb 14;451(7180):846-50. doi: 10.1038/nature06546. Nature. 2008. PMID: 18273021

9

Fungal Rtt109 histone acetyltransferase is an unexpected structural homolog of metazoan p300/CBP.

Tang Y, Holbert MA, Wurtele H, Meeth K, Rocha W, Gharib M, Jiang E, Thibault P, Verreault A, Cole PA, Marmorstein R. Tang Y, et al. Among authors: marmorstein r. Nat Struct Mol Biol. 2008 Jul;15(7):738-45. doi: 10.1038/nsmb.1448. Epub 2008 Jun 22. Nat Struct Mol Biol. 2008. PMID: 18568037 Free PMC article.

10

Structure and chemistry of the p300/CBP and Rtt109 histone acetyltransferases: implications for histone acetyltransferase evolution and function.

Wang L, Tang Y, Cole PA, Marmorstein R. Wang L, et al. Among authors: marmorstein r. Curr Opin Struct Biol. 2008 Dec;18(6):741-7. doi: 10.1016/j.sbi.2008.09.004. Epub 2008 Oct 27. Curr Opin Struct Biol. 2008. PMID: 18845255 Free PMC article. Review.

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