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Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt.
Zhang J, Xu K, Liu P, Geng Y, Wang B, Gan W, Guo J, Wu F, Chin YR, Berrios C, Lien EC, Toker A, DeCaprio JA, Sicinski P, Wei W. Zhang J, et al. Among authors: liu p. Mol Cell. 2016 Jun 16;62(6):929-942. doi: 10.1016/j.molcel.2016.04.023. Epub 2016 May 26. Mol Cell. 2016. PMID: 27237051 Free PMC article.
The mTOR-S6K pathway links growth signalling to DNA damage response by targeting RNF168.
Xie X, Hu H, Tong X, Li L, Liu X, Chen M, Yuan H, Xie X, Li Q, Zhang Y, Ouyang H, Wei M, Huang J, Liu P, Gan W, Liu Y, Xie A, Kuai X, Chirn GW, Zhou H, Zeng R, Hu R, Qin J, Meng FL, Wei W, Ji H, Gao D. Xie X, et al. Among authors: liu y, liu x, liu p. Nat Cell Biol. 2018 Mar;20(3):320-331. doi: 10.1038/s41556-017-0033-8. Epub 2018 Feb 5. Nat Cell Biol. 2018. PMID: 29403037 Free PMC article.
AKT methylation by SETDB1 promotes AKT kinase activity and oncogenic functions.
Guo J, Dai X, Laurent B, Zheng N, Gan W, Zhang J, Guo A, Yuan M, Liu P, Asara JM, Toker A, Shi Y, Pandolfi PP, Wei W. Guo J, et al. Among authors: liu p. Nat Cell Biol. 2019 Feb;21(2):226-237. doi: 10.1038/s41556-018-0261-6. Epub 2019 Jan 28. Nat Cell Biol. 2019. PMID: 30692625 Free PMC article.
Control of mTOR signaling by ubiquitin.
Jiang Y, Su S, Zhang Y, Qian J, Liu P. Jiang Y, et al. Among authors: liu p. Oncogene. 2019 May;38(21):3989-4001. doi: 10.1038/s41388-019-0713-x. Epub 2019 Jan 31. Oncogene. 2019. PMID: 30705402 Free PMC article. Review.
MERTK mediated novel site Akt phosphorylation alleviates SAV1 suppression.
Jiang Y, Zhang Y, Leung JY, Fan C, Popov KI, Su S, Qian J, Wang X, Holtzhausen A, Ubil E, Xiang Y, Davis I, Dokholyan NV, Wu G, Perou CM, Kim WY, Earp HS, Liu P. Jiang Y, et al. Among authors: liu p. Nat Commun. 2019 Apr 3;10(1):1515. doi: 10.1038/s41467-019-09233-7. Nat Commun. 2019. PMID: 30944303 Free PMC article.
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