The AMP analog AICAR modulates the Treg/Th17 axis through enhancement of fatty acid oxidation.
Gualdoni GA, Mayer KA, Göschl L, Boucheron N, Ellmeier W, Zlabinger GJ.
Gualdoni GA, et al. Among authors: goschl l.
FASEB J. 2016 Nov;30(11):3800-3809. doi: 10.1096/fj.201600522R. Epub 2016 Aug 4.
FASEB J. 2016.
PMID: 27492924
We provide a previously unrecognized insight into the delicate interplay between immune cell function and metabolism and delineate a potential novel strategy for metabolism-targeting immunotherapy.-Gualdoni, G. A., Mayer, K. A., Goschl, L., Boucheron, N., Ellmeier, …
We provide a previously unrecognized insight into the delicate interplay between immune cell function and metabolism and delineate a potenti …