van Roon JAG - Search Results

1

Systemic and local granzyme B levels are associated with disease activity, kidney damage and interferon signature in systemic lupus erythematosus.

Kok HM, van den Hoogen LL, van Roon JAG, Adriaansen EJM, Fritsch-Stork RDE, Nguyen TQ, Goldschmeding R, Radstake TRDJ, Bovenschen N. Kok HM, et al. Among authors: van roon jag, van den hoogen ll. Rheumatology (Oxford). 2017 Dec 1;56(12):2129-2134. doi: 10.1093/rheumatology/kex332. Rheumatology (Oxford). 2017. PMID: 28968826

2

Apocynin, a plant-derived, cartilage-saving drug, might be useful in the treatment of rheumatoid arthritis.

Lafeber FP, Beukelman CJ, van den Worm E, van Roy JL, Vianen ME, van Roon JA, van Dijk H, Bijlsma JW. Lafeber FP, et al. Rheumatology (Oxford). 1999 Nov;38(11):1088-93. doi: 10.1093/rheumatology/38.11.1088. Rheumatology (Oxford). 1999. PMID: 10556260

3

Fcgamma receptor expression levels on monocytes are elevated in rheumatoid arthritis patients with high erythrocyte sedimentation rate who do not use anti-rheumatic drugs.

Wijngaarden S, van Roon JA, Bijlsma JW, van de Winkel JG, Lafeber FP. Wijngaarden S, et al. Rheumatology (Oxford). 2003 May;42(5):681-8. doi: 10.1093/rheumatology/keg174. Rheumatology (Oxford). 2003. PMID: 12709546

4

Down-regulation of activating Fcgamma receptors on monocytes of patients with rheumatoid arthritis upon methotrexate treatment.

Wijngaarden S, van Roon JA, van de Winkel JG, Bijlsma JW, Lafeber FP. Wijngaarden S, et al. Rheumatology (Oxford). 2005 Jun;44(6):729-34. doi: 10.1093/rheumatology/keh583. Epub 2005 Mar 9. Rheumatology (Oxford). 2005. PMID: 15757966

5

Safety and efficacy of leflunomide in primary Sjögren's syndrome: a phase II pilot study.

van Woerkom JM, Kruize AA, Geenen R, van Roon EN, Goldschmeding R, Verstappen SM, van Roon JA, Bijlsma JW. van Woerkom JM, et al. Ann Rheum Dis. 2007 Aug;66(8):1026-32. doi: 10.1136/ard.2006.060905. Epub 2007 Jan 12. Ann Rheum Dis. 2007. PMID: 17223657 Free PMC article. Clinical Trial.

6

Numbers of CD25+Foxp3+ T cells that lack the IL-7 receptor are increased intra-articularly and have impaired suppressive function in RA patients.

van Roon JA, Hartgring SA, van der Wurff-Jacobs KM, Bijlsma JW, Lafeber FP. van Roon JA, et al. Rheumatology (Oxford). 2010 Nov;49(11):2084-9. doi: 10.1093/rheumatology/keq237. Epub 2010 Aug 6. Rheumatology (Oxford). 2010. PMID: 20693259

7

IL-7 drives Th1 and Th17 cytokine production in patients with primary SS despite an increase in CD4 T cells lacking the IL-7Rα.

Bikker A, Moret FM, Kruize AA, Bijlsma JW, Lafeber FP, van Roon JA. Bikker A, et al. Rheumatology (Oxford). 2012 Jun;51(6):996-1005. doi: 10.1093/rheumatology/ker448. Epub 2012 Feb 1. Rheumatology (Oxford). 2012. PMID: 22302060

8

Editorial: interleukin-7 and its receptor: the axis of evil to target in Sjögren's syndrome?

van Roon JA, Kruize AA, Radstake TR. van Roon JA, et al. Arthritis Rheum. 2013 Aug;65(8):1980-4. doi: 10.1002/art.38002. Arthritis Rheum. 2013. PMID: 23666552 Free article. No abstract available.

9

Targeting Th2-typified immune responses to prevent immunopathology in rheumatic diseases: belittled therapeutic strategies?

Moret FM, Radstake TR, van Roon JA. Moret FM, et al. Ann Rheum Dis. 2014 Mar;73(3):477-9. doi: 10.1136/annrheumdis-2013-204285. Epub 2013 Dec 9. Ann Rheum Dis. 2014. PMID: 24323396 No abstract available.

10

Overlapping gene expression profiles indicative of antigen processing and the interferon pathway characterize inflammatory fibrotic skin diseases.

Limpers A, van Royen-Kerkhof A, van Roon JA, Radstake TR, Broen JC. Limpers A, et al. Expert Rev Clin Immunol. 2014 Feb;10(2):231-41. doi: 10.1586/1744666X.2014.872561. Epub 2014 Jan 2. Expert Rev Clin Immunol. 2014. PMID: 24382112 Review.

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