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Page 1
TORC1 organized in inhibited domains (TOROIDs) regulate TORC1 activity.
Prouteau M, Desfosses A, Sieben C, Bourgoint C, Lydia Mozaffari N, Demurtas D, Mitra AK, Guichard P, Manley S, Loewith R. Prouteau M, et al. Among authors: bourgoint c. Nature. 2017 Oct 12;550(7675):265-269. doi: 10.1038/nature24021. Epub 2017 Oct 4. Nature. 2017. PMID: 28976958 Free PMC article.
TORC2 controls endocytosis through plasma membrane tension.
Riggi M, Bourgoint C, Macchione M, Matile S, Loewith R, Roux A. Riggi M, et al. Among authors: bourgoint c. J Cell Biol. 2019 Jul 1;218(7):2265-2276. doi: 10.1083/jcb.201901096. Epub 2019 May 23. J Cell Biol. 2019. PMID: 31123183 Free PMC article.
Chemical Genetics of AGC-kinases Reveals Shared Targets of Ypk1, Protein Kinase A and Sch9.
Plank M, Perepelkina M, Müller M, Vaga S, Zou X, Bourgoint C, Berti M, Saarbach J, Haesendonckx S, Winssinger N, Aebersold R, Loewith R. Plank M, et al. Among authors: bourgoint c. Mol Cell Proteomics. 2020 Apr;19(4):655-671. doi: 10.1074/mcp.RA120.001955. Epub 2020 Feb 26. Mol Cell Proteomics. 2020. PMID: 32102971 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 33451700
EGOC inhibits TOROID polymerization by structurally activating TORC1.
Prouteau M, Bourgoint C, Felix J, Bonadei L, Sadian Y, Gabus C, Savvides SN, Gutsche I, Desfosses A, Loewith R. Prouteau M, et al. Among authors: bourgoint c. Nat Struct Mol Biol. 2023 Mar;30(3):273-285. doi: 10.1038/s41594-022-00912-6. Epub 2023 Jan 26. Nat Struct Mol Biol. 2023. PMID: 36702972 Free PMC article.