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Identification of novel PI3K inhibitors through a scaffold hopping strategy.
Martínez González S, Hernández AI, Álvarez RM, Rodríguez A, Ramos-Lima F, Bischoff JR, Albarrán MI, Cebriá A, Hernández-Encinas E, García-Arocha J, Cebrián D, Blanco-Aparicio C, Pastor J. Martínez González S, et al. Among authors: rodriguez a. Bioorg Med Chem Lett. 2017 Nov 1;27(21):4794-4799. doi: 10.1016/j.bmcl.2017.09.059. Epub 2017 Sep 30. Bioorg Med Chem Lett. 2017. PMID: 29017786
Identification of ETP-46321, a potent and orally bioavailable PI3K α, δ inhibitor.
Martínez González S, Hernández AI, Varela C, Rodríguez-Arístegui S, Lorenzo M, Rodríguez A, Rivero V, Martín JI, Saluste CG, Ramos-Lima F, Cendón E, Cebrián D, Aguirre E, Gomez-Casero E, Albarrán M, Alfonso P, García-Serelde B, Oyarzabal J, Rabal O, Mulero F, Gonzalez-Granda T, Link W, Fominaya J, Barbacid M, Bischoff JR, Pizcueta P, Pastor J. Martínez González S, et al. Among authors: rodriguez a, rodriguez aristegui s. Bioorg Med Chem Lett. 2012 May 15;22(10):3460-6. doi: 10.1016/j.bmcl.2012.03.090. Epub 2012 Mar 29. Bioorg Med Chem Lett. 2012. PMID: 22520259
The adaptor protein Miro1 modulates horizontal transfer of mitochondria in mouse melanoma models.
Novak J, Nahacka Z, Oliveira GL, Brisudova P, Dubisova M, Dvorakova S, Miklovicova S, Dalecka M, Puttrich V, Grycova L, Magalhaes-Novais S, Correia CM, Levoux J, Stepanek L, Prochazka J, Svec D, Reguera DP, Lopez-Domenech G, Zobalova R, Sedlacek R, Terp MG, Gammage PA, Lansky Z, Kittler J, Oliveira PJ, Ditzel HJ, Berridge MV, Rodriguez AM, Boukalova S, Rohlena J, Neuzil J. Novak J, et al. Among authors: rodriguez am. Cell Rep. 2025 Jan 9;44(1):115154. doi: 10.1016/j.celrep.2024.115154. Online ahead of print. Cell Rep. 2025. PMID: 39792553
Racism and Postpartum Blood Pressure in a Multiethnic Prospective Cohort.
Janevic T, Howell FM, Burdick M, Nowlin S, Maru S, Boychuk N, Oshewa O, Monterroso M, McCarthy K, Gundersen DA, Rodriguez A, Katzenstein C, Longley R, Whilby KW, Lee A, Cabrera C, Lewey J, Howell EA, Levine LD. Janevic T, et al. Among authors: rodriguez a. Hypertension. 2025 Jan 9. doi: 10.1161/HYPERTENSIONAHA.124.23772. Online ahead of print. Hypertension. 2025. PMID: 39781708
Efficacy outcomes of CDK4/6 inhibitors in combination with endocrine therapy treatment in hormone receptor-positive/HER2-negative advanced breast cancer according to PAM50 intrinsic subtype: Primary results of SOLTI-1801 CDK-PREDICT study.
Tolosa P, Pascual T, Martínez-Saez O, Hernando C, Servitja S, Fernández Abad M, Brasó-Maristany F, Sanfeliu E, Benitez Fuentes JD, Lema L, Ruano Y, García-Fructuoso I, Parrilla L, Rodríguez A, Roncero AM, Cobos MÁ, Sánchez-Bayona R, Alva M, Madariaga A, Villacampa G, Canes J, Salvador F, Sánchez-Belmonte A, Malumbres M, Prat A, Ciruelos E. Tolosa P, et al. Among authors: rodriguez a. Eur J Cancer. 2025 Jan 3:115219. doi: 10.1016/j.ejca.2024.115219. Online ahead of print. Eur J Cancer. 2025. PMID: 39779447
8,210 results