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Long-acting MIC-1/GDF15 molecules to treat obesity: Evidence from mice to monkeys.
Xiong Y, Walker K, Min X, Hale C, Tran T, Komorowski R, Yang J, Davda J, Nuanmanee N, Kemp D, Wang X, Liu H, Miller S, Lee KJ, Wang Z, Véniant MM. Xiong Y, et al. Among authors: lee kj. Sci Transl Med. 2017 Oct 18;9(412):eaan8732. doi: 10.1126/scitranslmed.aan8732. Sci Transl Med. 2017. PMID: 29046435
Generation of novel long-acting globular adiponectin molecules.
Ge H, Xiong Y, Lemon B, Lee KJ, Tang J, Wang P, Weiszmann J, Hawkins N, Laudemann J, Min X, Penny D, Wolfe T, Liu Q, Zhang R, Yeh WC, Shen W, Lindberg R, Wang Z, Sheng J, Li Y. Ge H, et al. Among authors: lee kj. J Mol Biol. 2010 May 28;399(1):113-9. doi: 10.1016/j.jmb.2010.03.062. Epub 2010 Apr 9. J Mol Biol. 2010. PMID: 20382165
Inhibition of secreted frizzled-related protein 5 improves glucose metabolism.
Rulifson IC, Majeti JZ, Xiong Y, Hamburger A, Lee KJ, Miao L, Lu M, Gardner J, Gong Y, Wu H, Case R, Yeh WC, Richards WG, Baribault H, Li Y. Rulifson IC, et al. Among authors: lee kj. Am J Physiol Endocrinol Metab. 2014 Dec 15;307(12):E1144-52. doi: 10.1152/ajpendo.00283.2014. Epub 2014 Nov 4. Am J Physiol Endocrinol Metab. 2014. PMID: 25370851 Free article.
Trefoil Factor 3 (TFF3) Is Regulated by Food Intake, Improves Glucose Tolerance and Induces Mucinous Metaplasia.
Ge H, Gardner J, Wu X, Rulifson I, Wang J, Xiong Y, Ye J, Belouski E, Cao P, Tang J, Lee KJ, Coberly S, Wu X, Gupte J, Miao L, Yang L, Nguyen N, Shan B, Yeh WC, Véniant MM, Li Y, Baribault H. Ge H, et al. Among authors: lee kj. PLoS One. 2015 Jun 17;10(6):e0126924. doi: 10.1371/journal.pone.0126924. eCollection 2015. PLoS One. 2015. PMID: 26083576 Free PMC article.
A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates.
Chan JC, Piper DE, Cao Q, Liu D, King C, Wang W, Tang J, Liu Q, Higbee J, Xia Z, Di Y, Shetterly S, Arimura Z, Salomonis H, Romanow WG, Thibault ST, Zhang R, Cao P, Yang XP, Yu T, Lu M, Retter MW, Kwon G, Henne K, Pan O, Tsai MM, Fuchslocher B, Yang E, Zhou L, Lee KJ, Daris M, Sheng J, Wang Y, Shen WD, Yeh WC, Emery M, Walker NP, Shan B, Schwarz M, Jackson SM. Chan JC, et al. Among authors: lee kj. Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9820-5. doi: 10.1073/pnas.0903849106. Epub 2009 May 14. Proc Natl Acad Sci U S A. 2009. PMID: 19443683 Free PMC article.
3,728 results