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Long-acting MIC-1/GDF15 molecules to treat obesity: Evidence from mice to monkeys.
Xiong Y, Walker K, Min X, Hale C, Tran T, Komorowski R, Yang J, Davda J, Nuanmanee N, Kemp D, Wang X, Liu H, Miller S, Lee KJ, Wang Z, Véniant MM. Xiong Y, et al. Among authors: nuanmanee n. Sci Transl Med. 2017 Oct 18;9(412):eaan8732. doi: 10.1126/scitranslmed.aan8732. Sci Transl Med. 2017. PMID: 29046435
Treating diabetes and obesity with an FGF21-mimetic antibody activating the βKlotho/FGFR1c receptor complex.
Foltz IN, Hu S, King C, Wu X, Yang C, Wang W, Weiszmann J, Stevens J, Chen JS, Nuanmanee N, Gupte J, Komorowski R, Sekirov L, Hager T, Arora T, Ge H, Baribault H, Wang F, Sheng J, Karow M, Wang M, Luo Y, McKeehan W, Wang Z, Véniant MM, Li Y. Foltz IN, et al. Among authors: nuanmanee n. Sci Transl Med. 2012 Nov 28;4(162):162ra153. doi: 10.1126/scitranslmed.3004690. Sci Transl Med. 2012. PMID: 23197570
Recombinant human lecithin-cholesterol acyltransferase Fc fusion: analysis of N- and O-linked glycans and identification and elimination of a xylose-based O-linked tetrasaccharide core in the linker region.
Spahr C, Kim JJ, Deng S, Kodama P, Xia Z, Tang J, Zhang R, Siu S, Nuanmanee N, Estes B, Stevens J, Zhou M, Lu HS. Spahr C, et al. Among authors: nuanmanee n. Protein Sci. 2013 Dec;22(12):1739-53. doi: 10.1002/pro.2373. Protein Sci. 2013. PMID: 24115046 Free PMC article.