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TNFR1 inhibition with a Nanobody protects against EAE development in mice.
Steeland S, Van Ryckeghem S, Van Imschoot G, De Rycke R, Toussaint W, Vanhoutte L, Vanhove C, De Vos F, Vandenbroucke RE, Libert C. Steeland S, et al. Among authors: libert c. Sci Rep. 2017 Oct 20;7(1):13646. doi: 10.1038/s41598-017-13984-y. Sci Rep. 2017. PMID: 29057962 Free PMC article.
IL-17 produced by Paneth cells drives TNF-induced shock.
Takahashi N, Vanlaere I, de Rycke R, Cauwels A, Joosten LA, Lubberts E, van den Berg WB, Libert C. Takahashi N, et al. Among authors: libert c. J Exp Med. 2008 Aug 4;205(8):1755-61. doi: 10.1084/jem.20080588. Epub 2008 Jul 28. J Exp Med. 2008. PMID: 18663129 Free PMC article.
The first MMP in sepsis.
Vandenbroucke RE, Dejager L, Libert C. Vandenbroucke RE, et al. Among authors: libert c. EMBO Mol Med. 2011 Jul;3(7):367-9. doi: 10.1002/emmm.201100146. Epub 2011 May 18. EMBO Mol Med. 2011. PMID: 21591260 Free PMC article. No abstract available.
Matrix metalloprotease 8-dependent extracellular matrix cleavage at the blood-CSF barrier contributes to lethality during systemic inflammatory diseases.
Vandenbroucke RE, Dejonckheere E, Van Lint P, Demeestere D, Van Wonterghem E, Vanlaere I, Puimège L, Van Hauwermeiren F, De Rycke R, Mc Guire C, Campestre C, López-Otin C, Matthys P, Leclercq G, Libert C. Vandenbroucke RE, et al. Among authors: libert c. J Neurosci. 2012 Jul 18;32(29):9805-16. doi: 10.1523/JNEUROSCI.0967-12.2012. J Neurosci. 2012. PMID: 22815495 Free PMC article.
319 results