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Page 1
ROS-induced near-homozygous genomes in thyroid cancer.
Corver WE, Demmers J, Oosting J, Sahraeian S, Boot A, Ruano D, Wezel TV, Morreau H. Corver WE, et al. Among authors: demmers j. Endocr Relat Cancer. 2018 Jan;25(1):83-97. doi: 10.1530/ERC-17-0288. Epub 2017 Oct 24. Endocr Relat Cancer. 2018. PMID: 29066502
Inhibition of epithelial cell migration and Src/FAK signaling by SIRT3.
Lee JJ, van de Ven RAH, Zaganjor E, Ng MR, Barakat A, Demmers JJPG, Finley LWS, Gonzalez Herrera KN, Hung YP, Harris IS, Jeong SM, Danuser G, McAllister SS, Haigis MC. Lee JJ, et al. Among authors: demmers jjpg. Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):7057-7062. doi: 10.1073/pnas.1800440115. Epub 2018 Jun 18. Proc Natl Acad Sci U S A. 2018. PMID: 29915029 Free PMC article.
STK19 drives transcription-coupled repair by stimulating repair complex stability, RNA Pol II ubiquitylation, and TFIIH recruitment.
Ramadhin AR, Lee SH, Zhou D, Salmazo A, Gonzalo-Hansen C, van Sluis M, Blom CMA, Janssens RC, Raams A, Dekkers D, Bezstarosti K, Slade D, Vermeulen W, Pines A, Demmers JAA, Bernecky C, Sixma TK, Marteijn JA. Ramadhin AR, et al. Among authors: demmers jaa. Mol Cell. 2024 Dec 19;84(24):4740-4757.e12. doi: 10.1016/j.molcel.2024.10.030. Epub 2024 Nov 14. Mol Cell. 2024. PMID: 39547223 Free article.
TCR-Engineered T Cells Directed against Ropporin-1 Constitute a Safe and Effective Treatment for Triple-Negative Breast Cancer.
Kortleve D, Hammerl D, van Brakel M, Wijers R, Roelofs D, Kroese K, Timmermans MM, Liao CY, Huang S, Trapman-Jansen A, Foekens R, Michaux J, de Beijer MTA, Buschow SI, Demmers JAA, Kok M, Danen EHJ, Bassani-Sternberg M, Martens JWM, Abbott RJM, Debets R. Kortleve D, et al. Among authors: demmers jaa. Cancer Discov. 2024 Dec 2;14(12):2450-2470. doi: 10.1158/2159-8290.CD-24-0168. Cancer Discov. 2024. PMID: 39172012 Free PMC article.
The small CRL4CSA ubiquitin ligase component DDA1 regulates transcription-coupled repair dynamics.
Llerena Schiffmacher DA, Lee SH, Kliza KW, Theil AF, Akita M, Helfricht A, Bezstarosti K, Gonzalo-Hansen C, van Attikum H, Verlaan-de Vries M, Vertegaal ACO, Hoeijmakers JHJ, Marteijn JA, Lans H, Demmers JAA, Vermeulen M, Sixma TK, Ogi T, Vermeulen W, Pines A. Llerena Schiffmacher DA, et al. Among authors: demmers jaa. Nat Commun. 2024 Jul 29;15(1):6374. doi: 10.1038/s41467-024-50584-7. Nat Commun. 2024. PMID: 39075067 Free PMC article.
Oncogene EVI1 drives acute myeloid leukemia via a targetable interaction with CTBP2.
Pastoors D, Havermans M, Mulet-Lazaro R, Brian D, Noort W, Grasel J, Hoogenboezem R, Smeenk L, Demmers JAA, Milsom MD, Enver T, Groen RWJ, Bindels E, Delwel R. Pastoors D, et al. Among authors: demmers jaa. Sci Adv. 2024 May 17;10(20):eadk9076. doi: 10.1126/sciadv.adk9076. Epub 2024 May 15. Sci Adv. 2024. PMID: 38748792 Free PMC article.
Transcription-coupled DNA-protein crosslink repair by CSB and CRL4CSA-mediated degradation.
van Sluis M, Yu Q, van der Woude M, Gonzalo-Hansen C, Dealy SC, Janssens RC, Somsen HB, Ramadhin AR, Dekkers DHW, Wienecke HL, Demmers JJPG, Raams A, Davó-Martínez C, Llerena Schiffmacher DA, van Toorn M, Häckes D, Thijssen KL, Zhou D, Lammers JG, Pines A, Vermeulen W, Pothof J, Demmers JAA, van den Berg DLC, Lans H, Marteijn JA. van Sluis M, et al. Among authors: demmers jjpg, demmers jaa. Nat Cell Biol. 2024 May;26(5):770-783. doi: 10.1038/s41556-024-01394-y. Epub 2024 Apr 10. Nat Cell Biol. 2024. PMID: 38600236 Free PMC article.
PCID2 dysregulates transcription and viral RNA processing to promote HIV-1 latency.
Crespo R, Ne E, Reinders J, Meier JIJ, Li C, Jansen S, Górska A, Koçer S, Kan TW, Doff W, Dekkers D, Demmers J, Palstra RJ, Rao S, Mahmoudi T. Crespo R, et al. Among authors: demmers j. iScience. 2024 Feb 6;27(3):109152. doi: 10.1016/j.isci.2024.109152. eCollection 2024 Mar 15. iScience. 2024. PMID: 38384833 Free PMC article.
215 results