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The Notch pathway inhibitor stapled α-helical peptide derived from mastermind-like 1 (SAHM1) abrogates the hallmarks of allergic asthma.
KleinJan A, Tindemans I, Montgomery JE, Lukkes M, de Bruijn MJW, van Nimwegen M, Bergen I, Moellering RE, Hoogsteden HC, Boon L, Amsen D, Hendriks RW. KleinJan A, et al. Among authors: lukkes m. J Allergy Clin Immunol. 2018 Jul;142(1):76-85.e8. doi: 10.1016/j.jaci.2017.08.042. Epub 2017 Oct 27. J Allergy Clin Immunol. 2018. PMID: 29111218 Free PMC article.
Increased surface expression of NOTCH on memory T cells in peripheral blood from patients with asthma.
Tindemans I, Vroman H, Lukkes M, van Nimwegen M, de Bruijn MJW, Li BWS, Kleinjan A, de Boer GM, Tramper-Stranders GA, Kool M, Braunstahl GJ, Hendriks RW. Tindemans I, et al. Among authors: lukkes m. J Allergy Clin Immunol. 2019 Feb;143(2):769-771.e3. doi: 10.1016/j.jaci.2018.09.012. Epub 2018 Oct 5. J Allergy Clin Immunol. 2019. PMID: 30296524 No abstract available.
Group 2 Innate Lymphoid Cells Exhibit a Dynamic Phenotype in Allergic Airway Inflammation.
Li BWS, Stadhouders R, de Bruijn MJW, Lukkes M, Beerens DMJM, Brem MD, KleinJan A, Bergen I, Vroman H, Kool M, van IJcken WFJ, Rao TN, Fehling HJ, Hendriks RW. Li BWS, et al. Among authors: lukkes m. Front Immunol. 2017 Dec 1;8:1684. doi: 10.3389/fimmu.2017.01684. eCollection 2017. Front Immunol. 2017. PMID: 29250067 Free PMC article.
A pathophysiological role of PDE3 in allergic airway inflammation.
Beute J, Lukkes M, Koekoek EP, Nastiti H, Ganesh K, de Bruijn MJ, Hockman S, van Nimwegen M, Braunstahl GJ, Boon L, Lambrecht BN, Manganiello VC, Hendriks RW, KleinJan A. Beute J, et al. Among authors: lukkes m. JCI Insight. 2018 Jan 25;3(2):e94888. doi: 10.1172/jci.insight.94888. eCollection 2018 Jan 25. JCI Insight. 2018. PMID: 29367458 Free PMC article.
16 results