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188 results

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Population pharmacokinetics of rifapentine and desacetyl rifapentine in healthy volunteers: nonlinearities in clearance and bioavailability.
Savic RM, Lu Y, Bliven-Sizemore E, Weiner M, Nuermberger E, Burman W, Dorman SE, Dooley KE. Savic RM, et al. Among authors: dooley ke. Antimicrob Agents Chemother. 2014 Jun;58(6):3035-42. doi: 10.1128/AAC.01918-13. Epub 2014 Mar 10. Antimicrob Agents Chemother. 2014. PMID: 24614383 Free PMC article. Clinical Trial.
Phase I safety, pharmacokinetics, and pharmacogenetics study of the antituberculosis drug PA-824 with concomitant lopinavir-ritonavir, efavirenz, or rifampin.
Dooley KE, Luetkemeyer AF, Park JG, Allen R, Cramer Y, Murray S, Sutherland D, Aweeka F, Koletar SL, Marzan F, Bao J, Savic R, Haas DW; AIDS Clinical Trials Group A5306 Study Team. Dooley KE, et al. Antimicrob Agents Chemother. 2014 Sep;58(9):5245-52. doi: 10.1128/AAC.03332-14. Epub 2014 Jun 23. Antimicrob Agents Chemother. 2014. PMID: 24957823 Free PMC article. Clinical Trial.
Quantification of rifapentine, a potent antituberculosis drug, from dried blood spot samples using liquid chromatographic-tandem mass spectrometric analysis.
Parsons TL, Marzinke MA, Hoang T, Bliven-Sizemore E, Weiner M, Mac Kenzie WR, Dorman SE, Dooley KE. Parsons TL, et al. Among authors: dooley ke. Antimicrob Agents Chemother. 2014 Nov;58(11):6747-57. doi: 10.1128/AAC.03607-14. Epub 2014 Sep 2. Antimicrob Agents Chemother. 2014. PMID: 25182637 Free PMC article. Clinical Trial.
Designing drug trials: considerations for pregnant women.
Sheffield JS, Siegel D, Mirochnick M, Heine RP, Nguyen C, Bergman KL, Savic RM, Long J, Dooley KE, Nesin M. Sheffield JS, et al. Among authors: dooley ke. Clin Infect Dis. 2014 Dec 15;59 Suppl 7(Suppl 7):S437-44. doi: 10.1093/cid/ciu709. Clin Infect Dis. 2014. PMID: 25425722 Free PMC article.
Novel dosing strategies increase exposures of the potent antituberculosis drug rifapentine but are poorly tolerated in healthy volunteers.
Dooley KE, Savic RM, Park JG, Cramer Y, Hafner R, Hogg E, Janik J, Marzinke MA, Patterson K, Benson CA, Hovind L, Dorman SE, Haas DW; ACTG A5311 Study Team. Dooley KE, et al. Antimicrob Agents Chemother. 2015;59(6):3399-405. doi: 10.1128/AAC.05128-14. Epub 2015 Mar 30. Antimicrob Agents Chemother. 2015. PMID: 25824215 Free PMC article. Clinical Trial.
188 results