Zhang X - Search Results

1

Pharmacokinetics, Pharmacodynamics, and Proposed Dosing of the Oral JAK1 and JAK2 Inhibitor Baricitinib in Pediatric and Young Adult CANDLE and SAVI Patients.

Kim H, Brooks KM, Tang CC, Wakim P, Blake M, Brooks SR, Montealegre Sanchez GA, de Jesus AA, Huang Y, Tsai WL, Gadina M, Prakash A, Janes JM, Zhang X, Macias WL, Kumar P, Goldbach-Mansky R. Kim H, et al. Among authors: zhang x. Clin Pharmacol Ther. 2018 Aug;104(2):364-373. doi: 10.1002/cpt.936. Epub 2017 Dec 8. Clin Pharmacol Ther. 2018. PMID: 29134648 Free PMC article.

2

Gatifloxacin pharmacokinetics in healthy men and women.

Zhang X, Overholser BR, Kays MB, Sowinski KM. Zhang X, et al. J Clin Pharmacol. 2006 Oct;46(10):1154-62. doi: 10.1177/0091270006291840. J Clin Pharmacol. 2006. PMID: 16988204 Clinical Trial.

3

Comparative pharmacokinetics studies of immediate- and modified-release formulations of glipizide in pigs and dogs.

Kulkarni R, Yumibe N, Wang Z, Zhang X, Tang CC, Ruterbories K, Cox A, McCain R, Knipp GT. Kulkarni R, et al. Among authors: zhang x. J Pharm Sci. 2012 Nov;101(11):4327-36. doi: 10.1002/jps.23292. Epub 2012 Aug 16. J Pharm Sci. 2012. PMID: 22899546

4

Prediction of Transporter-Mediated Drug-Drug Interactions for Baricitinib.

Posada MM, Cannady EA, Payne CD, Zhang X, Bacon JA, Pak YA, Higgins JW, Shahri N, Hall SD, Hillgren KM. Posada MM, et al. Among authors: zhang x. Clin Transl Sci. 2017 Nov;10(6):509-519. doi: 10.1111/cts.12486. Epub 2017 Jul 27. Clin Transl Sci. 2017. PMID: 28749581 Free PMC article. Clinical Trial.

5

Dose/Exposure-Response Modeling to Support Dosing Recommendation for Phase III Development of Baricitinib in Patients with Rheumatoid Arthritis.

Zhang X, Chua L, Ernest C 2nd, Macias W, Rooney T, Tham LS. Zhang X, et al. CPT Pharmacometrics Syst Pharmacol. 2017 Dec;6(12):804-813. doi: 10.1002/psp4.12251. Epub 2017 Oct 17. CPT Pharmacometrics Syst Pharmacol. 2017. PMID: 28891251 Free PMC article. Clinical Trial.

6

LY2963016 Insulin Glargine and Insulin Glargine (Lantus) Produce Comparable Pharmacokinetics and Pharmacodynamics at Two Dose Levels.

Zhang X, Lam ECQ, Seger ME, Coutant D, Chua L, Tan LH, Soon D, Linnebjerg H. Zhang X, et al. Clin Pharmacol Drug Dev. 2017 Nov;6(6):556-563. doi: 10.1002/cpdd.392. Epub 2017 Sep 21. Clin Pharmacol Drug Dev. 2017. PMID: 28940840 Clinical Trial.

7

Cardiovascular Safety During Treatment With Baricitinib in Rheumatoid Arthritis.

Taylor PC, Weinblatt ME, Burmester GR, Rooney TP, Witt S, Walls CD, Issa M, Salinas CA, Saifan C, Zhang X, Cardoso A, González-Gay MA, Takeuchi T. Taylor PC, et al. Among authors: zhang x. Arthritis Rheumatol. 2019 Jul;71(7):1042-1055. doi: 10.1002/art.40841. Epub 2019 May 25. Arthritis Rheumatol. 2019. PMID: 30663869 Free PMC article.

8

Comparison of baricitinib, upadacitinib, and tofacitinib mediated regulation of cytokine signaling in human leukocyte subpopulations.

McInnes IB, Byers NL, Higgs RE, Lee J, Macias WL, Na S, Ortmann RA, Rocha G, Rooney TP, Wehrman T, Zhang X, Zuckerman SH, Taylor PC. McInnes IB, et al. Among authors: zhang x. Arthritis Res Ther. 2019 Aug 2;21(1):183. doi: 10.1186/s13075-019-1964-1. Arthritis Res Ther. 2019. PMID: 31375130 Free PMC article.

9

Pharmacokinetics, Safety, and Tolerability of Single- and Multiple-Dose Once-Daily Baricitinib in Healthy Chinese Subjects: A Randomized Placebo-Controlled Study.

Zhao X, Sheng XY, Payne CD, Zhang X, Wang F, Cui YM. Zhao X, et al. Among authors: zhang x. Clin Pharmacol Drug Dev. 2020 Nov;9(8):952-960. doi: 10.1002/cpdd.868. Epub 2020 Sep 17. Clin Pharmacol Drug Dev. 2020. PMID: 32945153 Free PMC article. Clinical Trial.

10

Mirikizumab Exposure-Response Relationships in Patients with Moderately-to-Severely Active Ulcerative Colitis in Randomized Phase II and III Studies.

Friedrich S, Chua L, Adams DH, Crandall W, Zhang XC. Friedrich S, et al. Clin Pharmacol Ther. 2024 Aug;116(2):435-447. doi: 10.1002/cpt.3305. Epub 2024 May 26. Clin Pharmacol Ther. 2024. PMID: 38797892 Clinical Trial.

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