Hurst CD - Search Results

1

Genomic Subtypes of Non-invasive Bladder Cancer with Distinct Metabolic Profile and Female Gender Bias in KDM6A Mutation Frequency.

Hurst CD, Alder O, Platt FM, Droop A, Stead LF, Burns JE, Burghel GJ, Jain S, Klimczak LJ, Lindsay H, Roulson JA, Taylor CF, Thygesen H, Cameron AJ, Ridley AJ, Mott HR, Gordenin DA, Knowles MA. Hurst CD, et al. Cancer Cell. 2017 Nov 13;32(5):701-715.e7. doi: 10.1016/j.ccell.2017.08.005. Cancer Cell. 2017. PMID: 29136510 Free PMC article.

2

High-resolution analysis of genomic copy number alterations in bladder cancer by microarray-based comparative genomic hybridization.

Hurst CD, Fiegler H, Carr P, Williams S, Carter NP, Knowles MA. Hurst CD, et al. Oncogene. 2004 Mar 18;23(12):2250-63. doi: 10.1038/sj.onc.1207260. Oncogene. 2004. PMID: 14968109

3

FGFR3 and Ras gene mutations are mutually exclusive genetic events in urothelial cell carcinoma.

Jebar AH, Hurst CD, Tomlinson DC, Johnston C, Taylor CF, Knowles MA. Jebar AH, et al. Among authors: hurst cd. Oncogene. 2005 Aug 4;24(33):5218-25. doi: 10.1038/sj.onc.1208705. Oncogene. 2005. PMID: 15897885

4

DBC1 re-expression alters the expression of multiple components of the plasminogen pathway.

Louhelainen JP, Hurst CD, Pitt E, Nishiyama H, Pickett HA, Knowles MA. Louhelainen JP, et al. Among authors: hurst cd. Oncogene. 2006 Apr 13;25(16):2409-19. doi: 10.1038/sj.onc.1209228. Oncogene. 2006. PMID: 16369496

5

Expression of hTERT immortalises normal human urothelial cells without inactivation of the p16/Rb pathway.

Chapman EJ, Hurst CD, Pitt E, Chambers P, Aveyard JS, Knowles MA. Chapman EJ, et al. Among authors: hurst cd. Oncogene. 2006 Aug 17;25(36):5037-45. doi: 10.1038/sj.onc.1209513. Epub 2006 Apr 17. Oncogene. 2006. PMID: 16619045

6

Knockdown by shRNA identifies S249C mutant FGFR3 as a potential therapeutic target in bladder cancer.

Tomlinson DC, Hurst CD, Knowles MA. Tomlinson DC, et al. Among authors: hurst cd. Oncogene. 2007 Aug 30;26(40):5889-99. doi: 10.1038/sj.onc.1210399. Epub 2007 Mar 26. Oncogene. 2007. PMID: 17384684 Free PMC article.

7

Gene expression signatures predict outcome in non-muscle-invasive bladder carcinoma: a multicenter validation study.

Dyrskjøt L, Zieger K, Real FX, Malats N, Carrato A, Hurst C, Kotwal S, Knowles M, Malmström PU, de la Torre M, Wester K, Allory Y, Vordos D, Caillault A, Radvanyi F, Hein AM, Jensen JL, Jensen KM, Marcussen N, Orntoft TF. Dyrskjøt L, et al. Clin Cancer Res. 2007 Jun 15;13(12):3545-51. doi: 10.1158/1078-0432.CCR-06-2940. Clin Cancer Res. 2007. PMID: 17575217 Free article.

8

Inactivation of the Rb pathway and overexpression of both isoforms of E2F3 are obligate events in bladder tumours with 6p22 amplification.

Hurst CD, Tomlinson DC, Williams SV, Platt FM, Knowles MA. Hurst CD, et al. Oncogene. 2008 Apr 24;27(19):2716-27. doi: 10.1038/sj.onc.1210934. Epub 2007 Nov 26. Oncogene. 2008. PMID: 18037967 Free PMC article.

9

Papillary and muscle invasive bladder tumors with distinct genomic stability profiles have different DNA repair fidelity and KU DNA-binding activities.

Bentley J, L'Hôte C, Platt F, Hurst CD, Lowery J, Taylor C, Sak SC, Harnden P, Knowles MA, Kiltie AE. Bentley J, et al. Among authors: hurst cd. Genes Chromosomes Cancer. 2009 Apr;48(4):310-21. doi: 10.1002/gcc.20641. Genes Chromosomes Cancer. 2009. PMID: 19105236

10

A SNaPshot assay for the rapid and simple detection of four common hotspot codon mutations in the PIK3CA gene.

Hurst CD, Zuiverloon TC, Hafner C, Zwarthoff EC, Knowles MA. Hurst CD, et al. BMC Res Notes. 2009 Apr 29;2:66. doi: 10.1186/1756-0500-2-66. BMC Res Notes. 2009. PMID: 19402901 Free PMC article.

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