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Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa.
Huckins LM, Hatzikotoulas K, Southam L, Thornton LM, Steinberg J, Aguilera-McKay F, Treasure J, Schmidt U, Gunasinghe C, Romero A, Curtis C, Rhodes D, Moens J, Kalsi G, Dempster D, Leung R, Keohane A, Burghardt R, Ehrlich S, Hebebrand J, Hinney A, Ludolph A, Walton E, Deloukas P, Hofman A, Palotie A, Palta P, van Rooij FJA, Stirrups K, Adan R, Boni C, Cone R, Dedoussis G, van Furth E, Gonidakis F, Gorwood P, Hudson J, Kaprio J, Kas M, Keski-Rahkonen A, Kiezebrink K, Knudsen GP, Slof-Op 't Landt MCT, Maj M, Monteleone AM, Monteleone P, Raevuori AH, Reichborn-Kjennerud T, Tozzi F, Tsitsika A, van Elburg A; Eating Disorder Working Group of the Psychiatric Genomics Consortium; Collier DA, Sullivan PF, Breen G, Bulik CM, Zeggini E. Huckins LM, et al. Among authors: cone r. Mol Psychiatry. 2018 May;23(5):1169-1180. doi: 10.1038/mp.2017.88. Epub 2017 Jul 25. Mol Psychiatry. 2018. PMID: 29155802 Free PMC article.
Significant Locus and Metabolic Genetic Correlations Revealed in Genome-Wide Association Study of Anorexia Nervosa.
Duncan L, Yilmaz Z, Gaspar H, Walters R, Goldstein J, Anttila V, Bulik-Sullivan B, Ripke S; Eating Disorders Working Group of the Psychiatric Genomics Consortium; Thornton L, Hinney A, Daly M, Sullivan PF, Zeggini E, Breen G, Bulik CM. Duncan L, et al. Am J Psychiatry. 2017 Sep 1;174(9):850-858. doi: 10.1176/appi.ajp.2017.16121402. Epub 2017 May 12. Am J Psychiatry. 2017. PMID: 28494655 Free PMC article.
Novel Cocrystal Structures of Peptide Antagonists Bound to the Human Melanocortin Receptor 4 Unveil Unexplored Grounds for Structure-Based Drug Design.
Gimenez LE, Martin C, Yu J, Hollanders C, Hernandez CC, Wu Y, Yao D, Han GW, Dahir NS, Wu L, Van der Poorten O, Lamouroux A, Mannes M, Zhao S, Tourwé D, Stevens RC, Cone RD, Ballet S. Gimenez LE, et al. Among authors: cone rd. J Med Chem. 2024 Feb 22;67(4):2690-2711. doi: 10.1021/acs.jmedchem.3c01822. Epub 2024 Feb 12. J Med Chem. 2024. PMID: 38345933
Inhibition of the melanocortin-3 receptor (MC3R) causes generalized sensitization to anorectic agents.
Dahir NS, Gui Y, Wu Y, Sweeney PR, Williams SY, Gimenez LE, Sawyer TK, Joy ST, Mapp AK, Cone RD. Dahir NS, et al. Among authors: cone rd. bioRxiv [Preprint]. 2023 Dec 7:2023.12.05.570114. doi: 10.1101/2023.12.05.570114. bioRxiv. 2023. Update in: J Clin Invest. 2024 Jul 15;134(14):e178250. doi: 10.1172/JCI178250 PMID: 38106197 Free PMC article. Updated. Preprint.
615 results