Kutys ML - Search Results

1

A non-canonical Notch complex regulates adherens junctions and vascular barrier function.

Polacheck WJ, Kutys ML, Yang J, Eyckmans J, Wu Y, Vasavada H, Hirschi KK, Chen CS. Polacheck WJ, et al. Among authors: kutys ml. Nature. 2017 Dec 14;552(7684):258-262. doi: 10.1038/nature24998. Epub 2017 Nov 13. Nature. 2017. PMID: 29160307 Free PMC article.

2

Forces and mechanotransduction in 3D vascular biology.

Kutys ML, Chen CS. Kutys ML, et al. Curr Opin Cell Biol. 2016 Oct;42:73-79. doi: 10.1016/j.ceb.2016.04.011. Epub 2016 May 19. Curr Opin Cell Biol. 2016. PMID: 27209346 Free PMC article. Review.

3

Force Generation via β-Cardiac Myosin, Titin, and α-Actinin Drives Cardiac Sarcomere Assembly from Cell-Matrix Adhesions.

Chopra A, Kutys ML, Zhang K, Polacheck WJ, Sheng CC, Luu RJ, Eyckmans J, Hinson JT, Seidman JG, Seidman CE, Chen CS. Chopra A, et al. Among authors: kutys ml. Dev Cell. 2018 Jan 8;44(1):87-96.e5. doi: 10.1016/j.devcel.2017.12.012. Epub 2018 Jan 8. Dev Cell. 2018. PMID: 29316444 Free PMC article.

4

Microfabricated blood vessels for modeling the vascular transport barrier.

Polacheck WJ, Kutys ML, Tefft JB, Chen CS. Polacheck WJ, et al. Among authors: kutys ml. Nat Protoc. 2019 May;14(5):1425-1454. doi: 10.1038/s41596-019-0144-8. Epub 2019 Apr 5. Nat Protoc. 2019. PMID: 30953042 Free PMC article.

5

Extracellular matrix alignment dictates the organization of focal adhesions and directs uniaxial cell migration.

Wang WY, Pearson AT, Kutys ML, Choi CK, Wozniak MA, Baker BM, Chen CS. Wang WY, et al. Among authors: kutys ml. APL Bioeng. 2018 Dec 26;2(4):046107. doi: 10.1063/1.5052239. eCollection 2018 Dec. APL Bioeng. 2018. PMID: 31069329 Free PMC article.

6

Uncovering mutation-specific morphogenic phenotypes and paracrine-mediated vessel dysfunction in a biomimetic vascularized mammary duct platform.

Kutys ML, Polacheck WJ, Welch MK, Gagnon KA, Koorman T, Kim S, Li L, McClatchey AI, Chen CS. Kutys ML, et al. Nat Commun. 2020 Jul 6;11(1):3377. doi: 10.1038/s41467-020-17102-x. Nat Commun. 2020. PMID: 32632100 Free PMC article.

7

Microphysiological model of PIK3CA-driven vascular malformations reveals a role of dysregulated Rac1 and mTORC1/2 in lesion formation.

Aw WY, Cho C, Wang H, Cooper AH, Doherty EL, Rocco D, Huang SA, Kubik S, Whitworth CP, Armstrong R, Hickey AJ, Griffith B, Kutys ML, Blatt J, Polacheck WJ. Aw WY, et al. Among authors: kutys ml. Sci Adv. 2023 Feb 15;9(7):eade8939. doi: 10.1126/sciadv.ade8939. Epub 2023 Feb 15. Sci Adv. 2023. PMID: 36791204 Free PMC article.

8

Notch1 cortical signaling regulates epithelial architecture and cell-cell adhesion.

White MJ, Jacobs KA, Singh T, Mayo LN, Lin A, Chen CS, Jun YW, Kutys ML. White MJ, et al. Among authors: kutys ml. J Cell Biol. 2023 Dec 4;222(12):e202303013. doi: 10.1083/jcb.202303013. Epub 2023 Oct 5. J Cell Biol. 2023. PMID: 37796194 Free PMC article.

9

Adherens junctions organize size-selective proteolytic hotspots critical for Notch signalling.

Kwak M, Southard KM, Kim WR, Lin A, Kim NH, Gopalappa R, Lee HJ, An M, Choi SH, Jung Y, Noh K, Farlow J, Georgakopoulos A, Robakis NK, Kang MK, Kutys ML, Seo D, Kim HH, Kim YH, Cheon J, Gartner ZJ, Jun YW. Kwak M, et al. Among authors: kutys ml. Nat Cell Biol. 2022 Dec;24(12):1739-1753. doi: 10.1038/s41556-022-01031-6. Epub 2022 Dec 1. Nat Cell Biol. 2022. PMID: 36456828 Free PMC article.

10

An extracellular-matrix-specific GEF-GAP interaction regulates Rho GTPase crosstalk for 3D collagen migration.

Kutys ML, Yamada KM. Kutys ML, et al. Nat Cell Biol. 2014 Sep;16(9):909-17. doi: 10.1038/ncb3026. Epub 2014 Aug 24. Nat Cell Biol. 2014. PMID: 25150978 Free PMC article.

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