Orrú CD - Search Results

1

Prion seeding activity and infectivity in skin samples from patients with sporadic Creutzfeldt-Jakob disease.

Orrú CD, Yuan J, Appleby BS, Li B, Li Y, Winner D, Wang Z, Zhan YA, Rodgers M, Rarick J, Wyza RE, Joshi T, Wang GX, Cohen ML, Zhang S, Groveman BR, Petersen RB, Ironside JW, Quiñones-Mateu ME, Safar JG, Kong Q, Caughey B, Zou WQ. Orrú CD, et al. Sci Transl Med. 2017 Nov 22;9(417):eaam7785. doi: 10.1126/scitranslmed.aam7785. Sci Transl Med. 2017. PMID: 29167394 Free PMC article.

2

Human variant Creutzfeldt-Jakob disease and sheep scrapie PrP(res) detection using seeded conversion of recombinant prion protein.

Orrú CD, Wilham JM, Hughson AG, Raymond LD, McNally KL, Bossers A, Ligios C, Caughey B. Orrú CD, et al. Protein Eng Des Sel. 2009 Aug;22(8):515-21. doi: 10.1093/protein/gzp031. Epub 2009 Jul 1. Protein Eng Des Sel. 2009. PMID: 19570812 Free PMC article.

3

Rapid end-point quantitation of prion seeding activity with sensitivity comparable to bioassays.

Wilham JM, Orrú CD, Bessen RA, Atarashi R, Sano K, Race B, Meade-White KD, Taubner LM, Timmes A, Caughey B. Wilham JM, et al. Among authors: orru cd. PLoS Pathog. 2010 Dec 2;6(12):e1001217. doi: 10.1371/journal.ppat.1001217. PLoS Pathog. 2010. PMID: 21152012 Free PMC article.

4

Prion disease blood test using immunoprecipitation and improved quaking-induced conversion.

Orrú CD, Wilham JM, Raymond LD, Kuhn F, Schroeder B, Raeber AJ, Caughey B. Orrú CD, et al. mBio. 2011 May 10;2(3):e00078-11. doi: 10.1128/mBio.00078-11. Print 2011. mBio. 2011. PMID: 21558432 Free PMC article.

5

Prion seeded conversion and amplification assays.

Orrú CD, Caughey B. Orrú CD, et al. Top Curr Chem. 2011;305:121-33. doi: 10.1007/128_2011_184. Top Curr Chem. 2011. PMID: 21678135 Free PMC article. Review.

6

Sensitive and specific detection of sporadic Creutzfeldt-Jakob disease brain prion protein using real-time quaking-induced conversion.

Peden AH, McGuire LI, Appleford NEJ, Mallinson G, Wilham JM, Orrú CD, Caughey B, Ironside JW, Knight RS, Will RG, Green AJE, Head MW. Peden AH, et al. Among authors: orru cd. J Gen Virol. 2012 Feb;93(Pt 2):438-449. doi: 10.1099/vir.0.033365-0. Epub 2011 Oct 26. J Gen Virol. 2012. PMID: 22031526 Free PMC article.

7

Time course of prion seeding activity in cerebrospinal fluid of scrapie-infected hamsters after intratongue and intracerebral inoculations.

Orrù CD, Hughson AG, Race B, Raymond GJ, Caughey B. Orrù CD, et al. J Clin Microbiol. 2012 Apr;50(4):1464-6. doi: 10.1128/JCM.06099-11. Epub 2012 Jan 11. J Clin Microbiol. 2012. PMID: 22238438 Free PMC article.

8

New generation QuIC assays for prion seeding activity.

Orrù CD, Wilham JM, Vascellari S, Hughson AG, Caughey B. Orrù CD, et al. Prion. 2012 Apr-Jun;6(2):147-52. doi: 10.4161/pri.19430. Epub 2012 Apr 1. Prion. 2012. PMID: 22421206 Free PMC article. Review.

9

Real time quaking-induced conversion analysis of cerebrospinal fluid in sporadic Creutzfeldt-Jakob disease.

McGuire LI, Peden AH, Orrú CD, Wilham JM, Appleford NE, Mallinson G, Andrews M, Head MW, Caughey B, Will RG, Knight RS, Green AJ. McGuire LI, et al. Among authors: orru cd. Ann Neurol. 2012 Aug;72(2):278-85. doi: 10.1002/ana.23589. Ann Neurol. 2012. PMID: 22926858 Free PMC article.

10

Prion seeding activities of mouse scrapie strains with divergent PrPSc protease sensitivities and amyloid plaque content using RT-QuIC and eQuIC.

Vascellari S, Orrù CD, Hughson AG, King D, Barron R, Wilham JM, Baron GS, Race B, Pani A, Caughey B. Vascellari S, et al. Among authors: orru cd. PLoS One. 2012;7(11):e48969. doi: 10.1371/journal.pone.0048969. Epub 2012 Nov 5. PLoS One. 2012. PMID: 23139828 Free PMC article.

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