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Utility of Imaging-Based Biomarkers for Glutamate-Targeted Drug Development in Psychotic Disorders: A Randomized Clinical Trial.
Javitt DC, Carter CS, Krystal JH, Kantrowitz JT, Girgis RR, Kegeles LS, Ragland JD, Maddock RJ, Lesh TA, Tanase C, Corlett PR, Rothman DL, Mason G, Qiu M, Robinson J, Potter WZ, Carlson M, Wall MM, Choo TH, Grinband J, Lieberman JA. Javitt DC, et al. Among authors: carlson m. JAMA Psychiatry. 2018 Jan 1;75(1):11-19. doi: 10.1001/jamapsychiatry.2017.3572. JAMA Psychiatry. 2018. PMID: 29167877 Free PMC article. Clinical Trial.
A multicenter study of ketamine effects on functional connectivity: Large scale network relationships, hubs and symptom mechanisms.
Fleming LM, Javitt DC, Carter CS, Kantrowitz JT, Girgis RR, Kegeles LS, Ragland JD, Maddock RJ, Lesh TA, Tanase C, Robinson J, Potter WZ, Carlson M, Wall MM, Choo TH, Grinband J, Lieberman J, Krystal JH, Corlett PR. Fleming LM, et al. Among authors: carlson m. Neuroimage Clin. 2019;22:101739. doi: 10.1016/j.nicl.2019.101739. Epub 2019 Feb 28. Neuroimage Clin. 2019. PMID: 30852397 Free PMC article.
Significant improvement in treatment resistant auditory verbal hallucinations after 5 days of double-blind, randomized, sham controlled, fronto-temporal, transcranial direct current stimulation (tDCS): A replication/extension study.
Kantrowitz JT, Sehatpour P, Avissar M, Horga G, Gwak A, Hoptman MJ, Beggel O, Girgis RR, Vail B, Silipo G, Carlson M, Javitt DC. Kantrowitz JT, et al. Among authors: carlson m. Brain Stimul. 2019 Jul-Aug;12(4):981-991. doi: 10.1016/j.brs.2019.03.003. Epub 2019 Mar 5. Brain Stimul. 2019. PMID: 30922713 Free PMC article. Clinical Trial.
Double blind, two dose, randomized, placebo-controlled, cross-over clinical trial of the positive allosteric modulator at the alpha7 nicotinic cholinergic receptor AVL-3288 in schizophrenia patients.
Kantrowitz JT, Javitt DC, Freedman R, Sehatpour P, Kegeles LS, Carlson M, Sobeih T, Wall MM, Choo TH, Vail B, Grinband J, Lieberman JA. Kantrowitz JT, et al. Among authors: carlson m. Neuropsychopharmacology. 2020 Jul;45(8):1339-1345. doi: 10.1038/s41386-020-0628-9. Epub 2020 Feb 3. Neuropsychopharmacology. 2020. PMID: 32015461 Free PMC article. Clinical Trial.
Grant Report on d-Serine Augmentation of Neuroplasticity-Based Auditory Learning in Schizophrenia †.
de la Garrigue N, Glasser J, Sehatpour P, Iosifescu DV, Dias E, Carlson M, Shope C, Sobeih T, Choo TH, Wall MM, Kegeles LS, Gangwisch J, Mayer M, Brazis S, De Baun HM, Wolfer S, Bermudez D, Arnold M, Rette D, Meftah AM, Conant M, Lieberman JA, Kantrowitz JT. de la Garrigue N, et al. Among authors: carlson m. J Psychiatr Brain Sci. 2020;5(4):e200018. Epub 2020 Aug 6. J Psychiatr Brain Sci. 2020. PMID: 32856005 Free PMC article.
Dopamine D1R Receptor Stimulation as a Mechanistic Pro-cognitive Target for Schizophrenia.
Abi-Dargham A, Javitch JA, Slifstein M, Anticevic A, Calkins ME, Cho YT, Fonteneau C, Gil R, Girgis R, Gur RE, Gur RC, Grinband J, Kantrowitz J, Kohler C, Krystal J, Murray J, Ranganathan M, Santamauro N, Van Snellenberg J, Tamayo Z, Wolf D; TRANSCENDS Group; Gray D, Lieberman J. Abi-Dargham A, et al. Schizophr Bull. 2022 Jan 21;48(1):199-210. doi: 10.1093/schbul/sbab095. Schizophr Bull. 2022. PMID: 34423843 Free PMC article.
Mismatch negativity as an index of target engagement for excitation/inhibition-based treatment development: a double-blind, placebo-controlled, randomized, single-dose cross-over study of the serotonin type-3 receptor antagonist CVN058.
Sehatpour P, Javitt DC, De Baun HM, Carlson M, Beloborodova A, Margolin DH, Carlton MBL, Brice NL, Kantrowitz JT. Sehatpour P, et al. Among authors: carlson m. Neuropsychopharmacology. 2022 Feb;47(3):711-718. doi: 10.1038/s41386-021-01170-8. Epub 2021 Oct 20. Neuropsychopharmacology. 2022. PMID: 34667294 Free PMC article. Clinical Trial.
Dose-Dependent Augmentation of Neuroplasticity-Based Auditory Learning in Schizophrenia: A Double-Blind, Placebo-Controlled, Randomized, Target Engagement Clinical Trial of the NMDA Glutamate Receptor Agonist d-serine.
Sehatpour P, Iosifescu DV, De Baun HM, Shope C, Mayer MR, Gangwisch J, Dias E, Sobeih T, Choo TH, Wall MM, Medalia A, Saperstein AM, Kegeles LS, Girgis RR, Carlson M, Kantrowitz JT. Sehatpour P, et al. Among authors: carlson m. Biol Psychiatry. 2023 Jul 15;94(2):164-173. doi: 10.1016/j.biopsych.2023.01.015. Epub 2023 Jan 28. Biol Psychiatry. 2023. PMID: 36958998 Free PMC article. Clinical Trial.
Illness Phase as a Key Assessment and Intervention Window for Psychosis.
Kohler CG, Wolf DH, Abi-Dargham A, Anticevic A, Cho YT, Fonteneau C, Gil R, Girgis RR, Gray DL, Grinband J, Javitch JA, Kantrowitz JT, Krystal JH, Lieberman JA, Murray JD, Ranganathan M, Santamauro N, Van Snellenberg JX, Tamayo Z; TRANSCENDS Group; Gur RC, Gur RE, Calkins ME. Kohler CG, et al. Biol Psychiatry Glob Open Sci. 2022 Jun 18;3(3):340-350. doi: 10.1016/j.bpsgos.2022.05.009. eCollection 2023 Jul. Biol Psychiatry Glob Open Sci. 2022. PMID: 37519466 Free PMC article. Review.
2,091 results