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Page 1
Utility of Imaging-Based Biomarkers for Glutamate-Targeted Drug Development in Psychotic Disorders: A Randomized Clinical Trial.
Javitt DC, Carter CS, Krystal JH, Kantrowitz JT, Girgis RR, Kegeles LS, Ragland JD, Maddock RJ, Lesh TA, Tanase C, Corlett PR, Rothman DL, Mason G, Qiu M, Robinson J, Potter WZ, Carlson M, Wall MM, Choo TH, Grinband J, Lieberman JA. Javitt DC, et al. Among authors: potter wz. JAMA Psychiatry. 2018 Jan 1;75(1):11-19. doi: 10.1001/jamapsychiatry.2017.3572. JAMA Psychiatry. 2018. PMID: 29167877 Free PMC article. Clinical Trial.
A multicenter study of ketamine effects on functional connectivity: Large scale network relationships, hubs and symptom mechanisms.
Fleming LM, Javitt DC, Carter CS, Kantrowitz JT, Girgis RR, Kegeles LS, Ragland JD, Maddock RJ, Lesh TA, Tanase C, Robinson J, Potter WZ, Carlson M, Wall MM, Choo TH, Grinband J, Lieberman J, Krystal JH, Corlett PR. Fleming LM, et al. Among authors: potter wz. Neuroimage Clin. 2019;22:101739. doi: 10.1016/j.nicl.2019.101739. Epub 2019 Feb 28. Neuroimage Clin. 2019. PMID: 30852397 Free PMC article.
Proof of mechanism and target engagement of glutamatergic drugs for the treatment of schizophrenia: RCTs of pomaglumetad and TS-134 on ketamine-induced psychotic symptoms and pharmacoBOLD in healthy volunteers.
Kantrowitz JT, Grinband J, Goff DC, Lahti AC, Marder SR, Kegeles LS, Girgis RR, Sobeih T, Wall MM, Choo TH, Green MF, Yang YS, Lee J, Horga G, Krystal JH, Potter WZ, Javitt DC, Lieberman JA. Kantrowitz JT, et al. Among authors: potter wz. Neuropsychopharmacology. 2020 Oct;45(11):1842-1850. doi: 10.1038/s41386-020-0706-z. Epub 2020 May 13. Neuropsychopharmacology. 2020. PMID: 32403118 Free PMC article. Clinical Trial.
Translating glutamate: from pathophysiology to treatment.
Javitt DC, Schoepp D, Kalivas PW, Volkow ND, Zarate C, Merchant K, Bear MF, Umbricht D, Hajos M, Potter WZ, Lee CM. Javitt DC, et al. Among authors: potter wz. Sci Transl Med. 2011 Sep 28;3(102):102mr2. doi: 10.1126/scitranslmed.3002804. Sci Transl Med. 2011. PMID: 21957170 Free PMC article. Review.
Plasma norepinephrine in chronic schizophrenia.
Breier A, Wolkowitz OM, Roy A, Potter WZ, Pickar D. Breier A, et al. Among authors: potter wz. Am J Psychiatry. 1990 Nov;147(11):1467-70. doi: 10.1176/ajp.147.11.1467. Am J Psychiatry. 1990. PMID: 2221157
A randomized proof-of-mechanism trial applying the 'fast-fail' approach to evaluating κ-opioid antagonism as a treatment for anhedonia.
Krystal AD, Pizzagalli DA, Smoski M, Mathew SJ, Nurnberger J Jr, Lisanby SH, Iosifescu D, Murrough JW, Yang H, Weiner RD, Calabrese JR, Sanacora G, Hermes G, Keefe RSE, Song A, Goodman W, Szabo ST, Whitton AE, Gao K, Potter WZ. Krystal AD, et al. Among authors: potter wz. Nat Med. 2020 May;26(5):760-768. doi: 10.1038/s41591-020-0806-7. Epub 2020 Mar 30. Nat Med. 2020. PMID: 32231295 Free PMC article. Clinical Trial.
Biomarkers in psychotropic drug development.
Ahmed S, Mozley PD, Potter WZ. Ahmed S, et al. Among authors: potter wz. Am J Geriatr Psychiatry. 2002 Nov-Dec;10(6):678-86. Am J Geriatr Psychiatry. 2002. PMID: 12427576 Review.
Cerebrospinal fluid monoamine metabolites in childhood-onset schizophrenia.
Jacobsen LK, Frazier JA, Malhotra AK, Karoum F, McKenna K, Gordon CT, Hamburger SD, Lenane MC, Pickar D, Potter WZ, Rapoport JL. Jacobsen LK, et al. Among authors: potter wz. Am J Psychiatry. 1997 Jan;154(1):69-74. doi: 10.1176/ajp.154.1.69. Am J Psychiatry. 1997. PMID: 8988961
Selective kappa-opioid antagonism ameliorates anhedonic behavior: evidence from the Fast-fail Trial in Mood and Anxiety Spectrum Disorders (FAST-MAS).
Pizzagalli DA, Smoski M, Ang YS, Whitton AE, Sanacora G, Mathew SJ, Nurnberger J Jr, Lisanby SH, Iosifescu DV, Murrough JW, Yang H, Weiner RD, Calabrese JR, Goodman W, Potter WZ, Krystal AD. Pizzagalli DA, et al. Among authors: potter wz. Neuropsychopharmacology. 2020 Sep;45(10):1656-1663. doi: 10.1038/s41386-020-0738-4. Epub 2020 Jun 16. Neuropsychopharmacology. 2020. PMID: 32544925 Free PMC article.
327 results