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A rapid and simple HPLC-MS/MS method for the simultaneous quantification of valproic acid and its five metabolites in human plasma and application to study pharmacokinetic interaction in Chinese epilepsy patients.
Wen D, Chen Z, Yang C, Liu H, Li H, Chen J, Dai Q, Zhong G, Qin J, Ni G, Huang M, Zhou L, Wang X. Wen D, et al. Among authors: chen z, chen j. J Pharm Biomed Anal. 2018 Feb 5;149:448-456. doi: 10.1016/j.jpba.2017.11.042. Epub 2017 Nov 16. J Pharm Biomed Anal. 2018. PMID: 29169113
Development and validation of two LC-MS/MS methods to assay urinary tylerdipine hydrochloride and its metabolites in healthy Chinese subjects.
Tao M, Zhou S, Wang Y, Wang L, Zhao Y, Xie L, Chen J, Liu Y, Zhang H, Ou N, Wang G, Shao F, Aa J. Tao M, et al. Among authors: chen j. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Oct 1;1096:172-179. doi: 10.1016/j.jchromb.2018.08.017. Epub 2018 Aug 21. J Chromatogr B Analyt Technol Biomed Life Sci. 2018. PMID: 30176506
A Randomized, Open-Label, Crossover Phase 1 Study to Evaluate the Effects of Food on the Pharmacokinetics of a Single Oral Dose of a 15-mg Tylerdipine Tablet in Healthy Chinese Male Volunteers.
Wang L, Xie L, Zhou S, Wang Y, Chen J, Zhou Y, Liu Y, Zhang H, Tao M, Ou N, Shao F. Wang L, et al. Among authors: chen j. Clin Pharmacol Drug Dev. 2019 Jan;8(1):126-132. doi: 10.1002/cpdd.622. Epub 2018 Oct 10. Clin Pharmacol Drug Dev. 2019. PMID: 30303628 Clinical Trial.
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