Chen W - Search Results

1

Highly Selective and Potent α4β2 nAChR Antagonist Inhibits Nicotine Self-Administration and Reinstatement in Rats.

Wu J, Cippitelli A, Zhang Y, Debevec G, Schoch J, Ozawa A, Yu Y, Liu H, Chen W, Houghten RA, Welmaker GS, Giulianotti MA, Toll L. Wu J, et al. Among authors: chen w. J Med Chem. 2017 Dec 28;60(24):10092-10104. doi: 10.1021/acs.jmedchem.7b01250. Epub 2017 Dec 13. J Med Chem. 2017. PMID: 29178785 Free PMC article.

2

XJW20, a novel oxoindole derivative, induces G2/M arrest and apoptosis selectively in K562 leukemia cell line.

Ye Z, Chen Z, Chen W, Xie J, Yang H, Lou Y, Yu Y. Ye Z, et al. Among authors: chen z, chen w. Chem Biol Interact. 2010 Jan 5;183(1):133-41. doi: 10.1016/j.cbi.2009.10.015. Chem Biol Interact. 2010. PMID: 19883635

3

Synthesis of polysubstituted 5-aminooxazoles from alpha-diazocarbonyl esters and alpha-isocyanoacetamides.

Wu J, Chen W, Hu M, Zou H, Yu Y. Wu J, et al. Among authors: chen w. Org Lett. 2010 Feb 5;12(3):616-8. doi: 10.1021/ol902850a. Org Lett. 2010. PMID: 20050600

4

Synthesis and antitumor evaluation of a novel class of 4-substituted-1,4-dihydroisoquinolin-3-ones.

Ma T, Chen W, Zhang G, Yu Y. Ma T, et al. Among authors: chen w. J Comb Chem. 2010 Jul 12;12(4):488-90. doi: 10.1021/cc100021t. J Comb Chem. 2010. PMID: 20426396

5

Domino approach for the synthesis of pyrrolo[1,2-alpha]pyrazine from vinyl azides.

Chen W, Hu M, Wu J, Zou H, Yu Y. Chen W, et al. Org Lett. 2010 Sep 3;12(17):3863-5. doi: 10.1021/ol101538x. Org Lett. 2010. PMID: 20677803

6

A novel method for the determination of isokinetic ratios and its application in the synthesis of two new positional scanning libraries.

Giulianotti MA, Debevec G, Santos RG, Maida LE, Chen W, Ou L, Yu Y, Dooley CT, Houghten RA. Giulianotti MA, et al. Among authors: chen w. ACS Comb Sci. 2012 Sep 10;14(9):503-12. doi: 10.1021/co300060s. Epub 2012 Aug 28. ACS Comb Sci. 2012. PMID: 22913403 Free PMC article.

7

Palladium-catalyzed C-H functionalization using guanidine as a directing group: ortho arylation and olefination of arylguanidines.

Shao J, Chen W, Giulianotti MA, Houghten RA, Yu Y. Shao J, et al. Among authors: chen w. Org Lett. 2012 Nov 2;14(21):5452-5. doi: 10.1021/ol302533w. Epub 2012 Oct 24. Org Lett. 2012. PMID: 23095022 Free PMC article.

8

One-pot three-component approach to the synthesis of polyfunctional pyrazoles.

Zhang G, Ni H, Chen W, Shao J, Liu H, Chen B, Yu Y. Zhang G, et al. Among authors: chen b, chen w. Org Lett. 2013 Dec 6;15(23):5967-9. doi: 10.1021/ol402810f. Epub 2013 Nov 20. Org Lett. 2013. PMID: 24255982

9

Libraries from Libraries: A Series of Sulfonamide Linked Heterocycles Derived from the Same Scaffold.

Debevec G, Chen W, Yu Y, Houghten RA, Giulianotti MA. Debevec G, et al. Among authors: chen w. Tetrahedron Lett. 2013 Aug 7;54(32):10.1016/j.tetlet.2013.06.003. doi: 10.1016/j.tetlet.2013.06.003. Tetrahedron Lett. 2013. PMID: 24363466 Free PMC article.

10

Design, Synthesis, and Biological Evaluation of Novel Conformationally Constrained Inhibitors Targeting EGFR.

Wu J, Chen W, Xia G, Zhang J, Shao J, Tan B, Zhang C, Yu W, Weng Q, Liu H, Hu M, Deng H, Hao Y, Shen J, Yu Y. Wu J, et al. Among authors: chen w. ACS Med Chem Lett. 2013 Aug 6;4(10):974-8. doi: 10.1021/ml4002437. eCollection 2013 Oct 10. ACS Med Chem Lett. 2013. PMID: 24900594 Free PMC article.

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