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Different pathways of molecular pathophysiology underlie cognitive and motor tauopathy phenotypes in transgenic models for Alzheimer's disease and frontotemporal lobar degeneration.
Melis V, Zabke C, Stamer K, Magbagbeolu M, Schwab K, Marschall P, Veh RW, Bachmann S, Deiana S, Moreau PH, Davidson K, Harrington KA, Rickard JE, Horsley D, Garman R, Mazurkiewicz M, Niewiadomska G, Wischik CM, Harrington CR, Riedel G, Theuring F. Melis V, et al. Among authors: horsley d. Cell Mol Life Sci. 2015 Jun;72(11):2199-222. doi: 10.1007/s00018-014-1804-z. Epub 2014 Dec 19. Cell Mol Life Sci. 2015. PMID: 25523019 Free PMC article.
Effects of oxidized and reduced forms of methylthioninium in two transgenic mouse tauopathy models.
Melis V, Magbagbeolu M, Rickard JE, Horsley D, Davidson K, Harrington KA, Goatman K, Goatman EA, Deiana S, Close SP, Zabke C, Stamer K, Dietze S, Schwab K, Storey JM, Harrington CR, Wischik CM, Theuring F, Riedel G. Melis V, et al. Among authors: horsley d. Behav Pharmacol. 2015 Jun;26(4):353-68. doi: 10.1097/FBP.0000000000000133. Behav Pharmacol. 2015. PMID: 25769090 Free PMC article.
A Protein Aggregation Inhibitor, Leuco-Methylthioninium Bis(Hydromethanesulfonate), Decreases α-Synuclein Inclusions in a Transgenic Mouse Model of Synucleinopathy.
Schwab K, Frahm S, Horsley D, Rickard JE, Melis V, Goatman EA, Magbagbeolu M, Douglas M, Leith MG, Baddeley TC, Storey JMD, Riedel G, Wischik CM, Harrington CR, Theuring F. Schwab K, et al. Among authors: horsley d. Front Mol Neurosci. 2018 Jan 10;10:447. doi: 10.3389/fnmol.2017.00447. eCollection 2017. Front Mol Neurosci. 2018. PMID: 29375308 Free PMC article.
Cellular Models of Aggregation-dependent Template-directed Proteolysis to Characterize Tau Aggregation Inhibitors for Treatment of Alzheimer Disease.
Harrington CR, Storey JM, Clunas S, Harrington KA, Horsley D, Ishaq A, Kemp SJ, Larch CP, Marshall C, Nicoll SL, Rickard JE, Simpson M, Sinclair JP, Storey LJ, Wischik CM. Harrington CR, et al. Among authors: horsley d. J Biol Chem. 2015 Apr 24;290(17):10862-75. doi: 10.1074/jbc.M114.616029. Epub 2015 Mar 10. J Biol Chem. 2015. PMID: 25759392 Free PMC article.
Conservation of heterochromatin protein 1 function.
Wang G, Ma A, Chow CM, Horsley D, Brown NR, Cowell IG, Singh PB. Wang G, et al. Among authors: horsley d. Mol Cell Biol. 2000 Sep;20(18):6970-83. doi: 10.1128/MCB.20.18.6970-6983.2000. Mol Cell Biol. 2000. PMID: 10958692 Free PMC article.
42 results