Whitman CP - Search Results

1

A global view of structure-function relationships in the tautomerase superfamily.

Davidson R, Baas BJ, Akiva E, Holliday GL, Polacco BJ, LeVieux JA, Pullara CR, Zhang YJ, Whitman CP, Babbitt PC. Davidson R, et al. Among authors: whitman cp. J Biol Chem. 2018 Feb 16;293(7):2342-2357. doi: 10.1074/jbc.M117.815340. Epub 2017 Nov 28. J Biol Chem. 2018. PMID: 29184004 Free PMC article.

2

4-Oxalocrotonate tautomerase, an enzyme composed of 62 amino acid residues per monomer.

Chen LH, Kenyon GL, Curtin F, Harayama S, Bembenek ME, Hajipour G, Whitman CP. Chen LH, et al. Among authors: whitman cp. J Biol Chem. 1992 Sep 5;267(25):17716-21. J Biol Chem. 1992. PMID: 1339435 Free article.

3

The crystal structure of YdcE, a 4-oxalocrotonate tautomerase homologue from Escherichia coli, confirms the structural basis for oligomer diversity.

Almrud JJ, Kern AD, Wang SC, Czerwinski RM, Johnson WH Jr, Murzin AG, Hackert ML, Whitman CP. Almrud JJ, et al. Among authors: whitman cp. Biochemistry. 2002 Oct 8;41(40):12010-24. doi: 10.1021/bi020271h. Biochemistry. 2002. PMID: 12356301

4

Mechanistic characterization of a bacterial malonate semialdehyde decarboxylase: identification of a new activity on the tautomerase superfamily.

Poelarends GJ, Johnson WH Jr, Murzin AG, Whitman CP. Poelarends GJ, et al. Among authors: whitman cp. J Biol Chem. 2003 Dec 5;278(49):48674-83. doi: 10.1074/jbc.M306706200. Epub 2003 Sep 23. J Biol Chem. 2003. PMID: 14506256 Free article.

5

The X-ray structure of trans-3-chloroacrylic acid dehalogenase reveals a novel hydration mechanism in the tautomerase superfamily.

de Jong RM, Brugman W, Poelarends GJ, Whitman CP, Dijkstra BW. de Jong RM, et al. Among authors: whitman cp. J Biol Chem. 2004 Mar 19;279(12):11546-52. doi: 10.1074/jbc.M311966200. Epub 2003 Dec 29. J Biol Chem. 2004. PMID: 14701869 Free article.

6

Evolution of enzymatic activity in the tautomerase superfamily: mechanistic and structural studies of the 1,3-dichloropropene catabolic enzymes.

Poelarends GJ, Whitman CP. Poelarends GJ, et al. Among authors: whitman cp. Bioorg Chem. 2004 Oct;32(5):376-92. doi: 10.1016/j.bioorg.2004.05.006. Bioorg Chem. 2004. PMID: 15381403 Review.

7

Inactivation of the phenylpyruvate tautomerase activity of macrophage migration inhibitory factor by 2-oxo-4-phenyl-3-butynoate.

Golubkov PA, Johnson WH Jr, Czerwinski RM, Person MD, Wang SC, Whitman CP, Hackert ML. Golubkov PA, et al. Among authors: whitman cp. Bioorg Chem. 2006 Aug;34(4):183-99. doi: 10.1016/j.bioorg.2006.05.001. Epub 2006 Jun 14. Bioorg Chem. 2006. PMID: 16780921

8

Evolution of enzymatic activity in the tautomerase superfamily: mechanistic and structural consequences of the L8R mutation in 4-oxalocrotonate tautomerase.

Poelarends GJ, Almrud JJ, Serrano H, Darty JE, Johnson WH Jr, Hackert ML, Whitman CP. Poelarends GJ, et al. Among authors: whitman cp. Biochemistry. 2006 Jun 27;45(25):7700-8. doi: 10.1021/bi0600603. Biochemistry. 2006. PMID: 16784221 Free PMC article.

9

Crystal structures of native and inactivated cis-3-chloroacrylic acid dehalogenase. Structural basis for substrate specificity and inactivation by (R)-oxirane-2-carboxylate.

de Jong RM, Bazzacco P, Poelarends GJ, Johnson WH Jr, Kim YJ, Burks EA, Serrano H, Thunnissen AM, Whitman CP, Dijkstra BW. de Jong RM, et al. Among authors: whitman cp. J Biol Chem. 2007 Jan 26;282(4):2440-9. doi: 10.1074/jbc.M608134200. Epub 2006 Nov 22. J Biol Chem. 2007. PMID: 17121835 Free article.

10

Kinetic and structural characterization of a heterohexamer 4-oxalocrotonate tautomerase from Chloroflexus aurantiacus J-10-fl: implications for functional and structural diversity in the tautomerase superfamily.

Burks EA, Fleming CD, Mesecar AD, Whitman CP, Pegan SD. Burks EA, et al. Among authors: whitman cp. Biochemistry. 2010 Jun 22;49(24):5016-27. doi: 10.1021/bi100502z. Biochemistry. 2010. PMID: 20465238 Free PMC article.

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