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Page 1
Inhibition of histone deacetylase 6 (HDAC6) protects against vincristine-induced peripheral neuropathies and inhibits tumor growth.
Van Helleputte L, Kater M, Cook DP, Eykens C, Rossaert E, Haeck W, Jaspers T, Geens N, Vanden Berghe P, Gysemans C, Mathieu C, Robberecht W, Van Damme P, Cavaletti G, Jarpe M, Van Den Bosch L. Van Helleputte L, et al. Among authors: rossaert e. Neurobiol Dis. 2018 Mar;111:59-69. doi: 10.1016/j.nbd.2017.11.011. Epub 2017 Nov 29. Neurobiol Dis. 2018. PMID: 29197621 Free article.
HDAC3 Inhibition Stimulates Myelination in a CMT1A Mouse Model.
Prior R, Verschoren S, Vints K, Jaspers T, Rossaert E, Klingl YE, Silva A, Hersmus N, Van Damme P, Van Den Bosch L. Prior R, et al. Among authors: rossaert e. Mol Neurobiol. 2022 Jun;59(6):3414-3430. doi: 10.1007/s12035-022-02782-x. Epub 2022 Mar 23. Mol Neurobiol. 2022. PMID: 35320455 Free PMC article.
Human motor units in microfluidic devices are impaired by FUS mutations and improved by HDAC6 inhibition.
Stoklund Dittlau K, Krasnow EN, Fumagalli L, Vandoorne T, Baatsen P, Kerstens A, Giacomazzi G, Pavie B, Rossaert E, Beckers J, Sampaolesi M, Van Damme P, Van Den Bosch L. Stoklund Dittlau K, et al. Among authors: rossaert e. Stem Cell Reports. 2021 Sep 14;16(9):2213-2227. doi: 10.1016/j.stemcr.2021.03.029. Epub 2021 Apr 22. Stem Cell Reports. 2021. PMID: 33891869 Free PMC article.
AAV9-mediated gene delivery of MCT1 to oligodendrocytes does not provide a therapeutic benefit in a mouse model of ALS.
Eykens C, Rossaert E, Duqué S, Rué L, Bento-Abreu A, Hersmus N, Lenaerts A, Kerstens A, Corthout N, Munck S, Van Damme P, Holt MG, von Jonquires G, Klugmann M, Van Den Bosch L, Robberecht W. Eykens C, et al. Among authors: rossaert e. Mol Ther Methods Clin Dev. 2021 Jan 20;20:508-519. doi: 10.1016/j.omtm.2021.01.006. eCollection 2021 Mar 12. Mol Ther Methods Clin Dev. 2021. PMID: 33614825 Free PMC article.
PMP22 duplication dysregulates lipid homeostasis and plasma membrane organization in developing human Schwann cells.
Prior R, Silva A, Vangansewinkel T, Idkowiak J, Tharkeshwar AK, Hellings TP, Michailidou I, Vreijling J, Loos M, Koopmans B, Vlek N, Agaser C, Kuipers TB, Michiels C, Rossaert E, Verschoren S, Vermeire W, de Laat V, Dehairs J, Eggermont K, van den Biggelaar D, Bademosi AT, Meunier FA, vandeVen M, Van Damme P, Mei H, Swinnen JV, Lambrichts I, Baas F, Fluiter K, Wolfs E, Van Den Bosch L. Prior R, et al. Among authors: rossaert e. Brain. 2024 Sep 3;147(9):3113-3130. doi: 10.1093/brain/awae158. Brain. 2024. PMID: 38743588 Free PMC article.