Cebers G - Search Results

1

Reversible and Species-Specific Depigmentation Effects of AZD3293, a BACE Inhibitor for the Treatment of Alzheimer's Disease, Are Related to BACE2 Inhibition and Confined to Epidermis and Hair.

Cebers G, Lejeune T, Attalla B, Soderberg M, Alexander RC, Budd Haeberlein S, Kugler AR, Ingersoll EW, Platz S, Scott CW. Cebers G, et al. J Prev Alzheimers Dis. 2016;3(4):202-218. doi: 10.14283/jpad.2016.119. J Prev Alzheimers Dis. 2016. PMID: 29199322

2

AZD3293: A Novel, Orally Active BACE1 Inhibitor with High Potency and Permeability and Markedly Slow Off-Rate Kinetics.

Eketjäll S, Janson J, Kaspersson K, Bogstedt A, Jeppsson F, Fälting J, Haeberlein SB, Kugler AR, Alexander RC, Cebers G. Eketjäll S, et al. Among authors: cebers g. J Alzheimers Dis. 2016;50(4):1109-23. doi: 10.3233/JAD-150834. J Alzheimers Dis. 2016. PMID: 26890753 Free PMC article.

3

AZD3293: Pharmacokinetic and Pharmacodynamic Effects in Healthy Subjects and Patients with Alzheimer's Disease.

Cebers G, Alexander RC, Haeberlein SB, Han D, Goldwater R, Ereshefsky L, Olsson T, Ye N, Rosen L, Russell M, Maltby J, Eketjäll S, Kugler AR. Cebers G, et al. J Alzheimers Dis. 2017;55(3):1039-1053. doi: 10.3233/JAD-160701. J Alzheimers Dis. 2017. PMID: 27767991 Clinical Trial.

4

Toward β-Secretase-1 Inhibitors with Improved Isoform Selectivity.

Johansson P, Kaspersson K, Gurrell IK, Bäck E, Eketjäll S, Scott CW, Cebers G, Thorne P, McKenzie MJ, Beaton H, Davey P, Kolmodin K, Holenz J, Duggan ME, Budd Haeberlein S, Bürli RW. Johansson P, et al. Among authors: cebers g. J Med Chem. 2018 Apr 26;61(8):3491-3502. doi: 10.1021/acs.jmedchem.7b01716. Epub 2018 Apr 10. J Med Chem. 2018. PMID: 29617572

5

Discovery of AZD3839, a potent and selective BACE1 inhibitor clinical candidate for the treatment of Alzheimer disease.

Jeppsson F, Eketjäll S, Janson J, Karlström S, Gustavsson S, Olsson LL, Radesäter AC, Ploeger B, Cebers G, Kolmodin K, Swahn BM, von Berg S, Bueters T, Fälting J. Jeppsson F, et al. Among authors: cebers g. J Biol Chem. 2012 Nov 30;287(49):41245-57. doi: 10.1074/jbc.M112.409110. Epub 2012 Oct 9. J Biol Chem. 2012. PMID: 23048024 Free PMC article.

6

The NMDA NR2B subunit-selective receptor antagonist, CP-101,606, enhances the functional recovery the NMDA NR2B subunit-selective receptor and reduces brain damage after cortical compression-induced brain ischemia.

Kundrotiene J, Cebers G, Wägner A, Liljequist S. Kundrotiene J, et al. Among authors: cebers g. J Neurotrauma. 2004 Jan;21(1):83-93. doi: 10.1089/089771504772695977. J Neurotrauma. 2004. PMID: 14987468

7

Glycine does not reverse the inhibitory actions of ethanol on NMDA receptor functions in cerebellar granule cells.

Cebers G, Cebere A, Zharkovsky A, Liljequist S. Cebers G, et al. Naunyn Schmiedebergs Arch Pharmacol. 1996 Dec;354(6):736-45. doi: 10.1007/BF00166900. Naunyn Schmiedebergs Arch Pharmacol. 1996. PMID: 8971734

8

Spermidine attenuates the inhibitory effect of ethanol on NMDA-induced neurotoxicity.

Cebere A, Cebers G, Wägner A, Liljequist S. Cebere A, et al. Among authors: cebers g. Naunyn Schmiedebergs Arch Pharmacol. 2002 Aug;366(2):117-22. doi: 10.1007/s00210-001-0513-y. Epub 2002 Jun 14. Naunyn Schmiedebergs Arch Pharmacol. 2002. PMID: 12122497

9

N-Methyl-D-aspartate-induced enhancement of activator protein-1 DNA binding activity is blocked by ethanol in cerebellar granule cells.

Hou YN, Cebers G, Cebere A, Terenius L, Liljequist S. Hou YN, et al. Among authors: cebers g. Eur J Pharmacol. 1996 Aug 15;309(3):307-10. doi: 10.1016/0014-2999(96)00438-4. Eur J Pharmacol. 1996. PMID: 8874155

10

Effects of decahydroisoquinoline-3-carboxylic acid monohydrate, a novel AMPA receptor antagonist, on glutamate-induced CA2+ responses and neurotoxicity in rat cortical and cerebellar granule neurons.

Liljequist S, Cebers G, Kalda A. Liljequist S, et al. Among authors: cebers g. Biochem Pharmacol. 1995 Nov 27;50(11):1761-74. doi: 10.1016/0006-2952(95)02032-2. Biochem Pharmacol. 1995. PMID: 8615854

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