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Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway.
Ollila S, Domènech-Moreno E, Laajanen K, Wong IP, Tripathi S, Pentinmikko N, Gao Y, Yan Y, Niemelä EH, Wang TC, Viollet B, Leone G, Katajisto P, Vaahtomeri K, Mäkelä TP. Ollila S, et al. Among authors: katajisto p. J Clin Invest. 2018 Jan 2;128(1):402-414. doi: 10.1172/JCI93597. Epub 2017 Dec 4. J Clin Invest. 2018. PMID: 29202476 Free PMC article.
Suppression of Peutz-Jeghers polyposis by inhibition of cyclooxygenase-2.
Udd L, Katajisto P, Rossi DJ, Lepistö A, Lahesmaa AM, Ylikorkala A, Järvinen HJ, Ristimäki AP, Mäkelä TP. Udd L, et al. Among authors: katajisto p. Gastroenterology. 2004 Oct;127(4):1030-7. doi: 10.1053/j.gastro.2004.07.059. Gastroenterology. 2004. PMID: 15480979
Mutation analysis of three genes encoding novel LKB1-interacting proteins, BRG1, STRADalpha, and MO25alpha, in Peutz-Jeghers syndrome.
Alhopuro P, Katajisto P, Lehtonen R, Ylisaukko-Oja SK, Näätsaari L, Karhu A, Westerman AM, Wilson JH, de Rooij FW, Vogel T, Moeslein G, Tomlinson IP, Aaltonen LA, Mäkelä TP, Launonen V. Alhopuro P, et al. Among authors: katajisto p. Br J Cancer. 2005 Mar 28;92(6):1126-9. doi: 10.1038/sj.bjc.6602454. Br J Cancer. 2005. PMID: 15756273 Free PMC article.
The LKB1 tumor suppressor kinase in human disease.
Katajisto P, Vallenius T, Vaahtomeri K, Ekman N, Udd L, Tiainen M, Mäkelä TP. Katajisto P, et al. Biochim Biophys Acta. 2007 Jan;1775(1):63-75. doi: 10.1016/j.bbcan.2006.08.003. Epub 2006 Aug 16. Biochim Biophys Acta. 2007. PMID: 17010524 Review.
Lkb1 is required for TGFbeta-mediated myofibroblast differentiation.
Vaahtomeri K, Ventelä E, Laajanen K, Katajisto P, Wipff PJ, Hinz B, Vallenius T, Tiainen M, Mäkelä TP. Vaahtomeri K, et al. Among authors: katajisto p. J Cell Sci. 2008 Nov 1;121(Pt 21):3531-40. doi: 10.1242/jcs.032706. Epub 2008 Oct 7. J Cell Sci. 2008. PMID: 18840652
Impaired gastric gland differentiation in Peutz-Jeghers syndrome.
Udd L, Katajisto P, Kyyrönen M, Ristimäki AP, Mäkelä TP. Udd L, et al. Among authors: katajisto p. Am J Pathol. 2010 May;176(5):2467-76. doi: 10.2353/ajpath.2010.090519. Epub 2010 Apr 2. Am J Pathol. 2010. PMID: 20363912 Free PMC article.
46 results