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PKA phosphorylates and inactivates AMPKalpha to promote efficient lipolysis.
Djouder N, Tuerk RD, Suter M, Salvioni P, Thali RF, Scholz R, Vaahtomeri K, Auchli Y, Rechsteiner H, Brunisholz RA, Viollet B, Mäkelä TP, Wallimann T, Neumann D, Krek W. Djouder N, et al. Among authors: viollet b. EMBO J. 2010 Jan 20;29(2):469-81. doi: 10.1038/emboj.2009.339. Epub 2009 Nov 26. EMBO J. 2010. PMID: 19942859 Free PMC article.
The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation.
Green AS, Chapuis N, Maciel TT, Willems L, Lambert M, Arnoult C, Boyer O, Bardet V, Park S, Foretz M, Viollet B, Ifrah N, Dreyfus F, Hermine O, Moura IC, Lacombe C, Mayeux P, Bouscary D, Tamburini J. Green AS, et al. Among authors: viollet b. Blood. 2010 Nov 18;116(20):4262-73. doi: 10.1182/blood-2010-02-269837. Epub 2010 Jul 28. Blood. 2010. PMID: 20668229 Free article.
The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver.
Patel K, Foretz M, Marion A, Campbell DG, Gourlay R, Boudaba N, Tournier E, Titchenell P, Peggie M, Deak M, Wan M, Kaestner KH, Göransson O, Viollet B, Gray NS, Birnbaum MJ, Sutherland C, Sakamoto K. Patel K, et al. Among authors: viollet b. Nat Commun. 2014 Aug 4;5:4535. doi: 10.1038/ncomms5535. Nat Commun. 2014. PMID: 25088745 Free PMC article.
358 results