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Page 1
Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope.
Cole DK, Fuller A, Dolton G, Zervoudi E, Legut M, Miles K, Blanchfield L, Madura F, Holland CJ, Bulek AM, Bridgeman JS, Miles JJ, Schauenburg AJA, Beck K, Evavold BD, Rizkallah PJ, Sewell AK. Cole DK, et al. Among authors: miles k, miles jj. Front Immunol. 2017 Nov 10;8:1503. doi: 10.3389/fimmu.2017.01503. eCollection 2017. Front Immunol. 2017. PMID: 29209312 Free PMC article.
MHC class I molecules with Superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs.
Wooldridge L, Clement M, Lissina A, Edwards ES, Ladell K, Ekeruche J, Hewitt RE, Laugel B, Gostick E, Cole DK, Debets R, Berrevoets C, Miles JJ, Burrows SR, Price DA, Sewell AK. Wooldridge L, et al. Among authors: miles jj. J Immunol. 2010 Apr 1;184(7):3357-66. doi: 10.4049/jimmunol.0902398. Epub 2010 Feb 26. J Immunol. 2010. PMID: 20190139 Free PMC article.
Anti-CD8 antibodies can trigger CD8+ T cell effector function in the absence of TCR engagement and improve peptide-MHCI tetramer staining.
Clement M, Ladell K, Ekeruche-Makinde J, Miles JJ, Edwards ES, Dolton G, Williams T, Schauenburg AJ, Cole DK, Lauder SN, Gallimore AM, Godkin AJ, Burrows SR, Price DA, Sewell AK, Wooldridge L. Clement M, et al. Among authors: miles jj. J Immunol. 2011 Jul 15;187(2):654-63. doi: 10.4049/jimmunol.1003941. Epub 2011 Jun 15. J Immunol. 2011. PMID: 21677135 Free PMC article.
A single autoimmune T cell receptor recognizes more than a million different peptides.
Wooldridge L, Ekeruche-Makinde J, van den Berg HA, Skowera A, Miles JJ, Tan MP, Dolton G, Clement M, Llewellyn-Lacey S, Price DA, Peakman M, Sewell AK. Wooldridge L, et al. Among authors: miles jj. J Biol Chem. 2012 Jan 6;287(2):1168-77. doi: 10.1074/jbc.M111.289488. Epub 2011 Nov 18. J Biol Chem. 2012. PMID: 22102287 Free PMC article.
Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Bulek AM, Cole DK, Skowera A, Dolton G, Gras S, Madura F, Fuller A, Miles JJ, Gostick E, Price DA, Drijfhout JW, Knight RR, Huang GC, Lissin N, Molloy PE, Wooldridge L, Jakobsen BK, Rossjohn J, Peakman M, Rizkallah PJ, Sewell AK. Bulek AM, et al. Among authors: miles jj. Nat Immunol. 2012 Jan 15;13(3):283-9. doi: 10.1038/ni.2206. Nat Immunol. 2012. PMID: 22245737 Free PMC article.
170 results