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Page 1
Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope.
Cole DK, Fuller A, Dolton G, Zervoudi E, Legut M, Miles K, Blanchfield L, Madura F, Holland CJ, Bulek AM, Bridgeman JS, Miles JJ, Schauenburg AJA, Beck K, Evavold BD, Rizkallah PJ, Sewell AK. Cole DK, et al. Among authors: miles k, miles jj. Front Immunol. 2017 Nov 10;8:1503. doi: 10.3389/fimmu.2017.01503. eCollection 2017. Front Immunol. 2017. PMID: 29209312 Free PMC article.
Peptide length determines the outcome of TCR/peptide-MHCI engagement.
Ekeruche-Makinde J, Miles JJ, van den Berg HA, Skowera A, Cole DK, Dolton G, Schauenburg AJ, Tan MP, Pentier JM, Llewellyn-Lacey S, Miles KM, Bulek AM, Clement M, Williams T, Trimby A, Bailey M, Rizkallah P, Rossjohn J, Peakman M, Price DA, Burrows SR, Sewell AK, Wooldridge L. Ekeruche-Makinde J, et al. Among authors: miles km, miles jj. Blood. 2013 Feb 14;121(7):1112-23. doi: 10.1182/blood-2012-06-437202. Epub 2012 Dec 18. Blood. 2013. PMID: 23255554 Free PMC article.
T-cell receptor specificity maintained by altered thermodynamics.
Madura F, Rizkallah PJ, Miles KM, Holland CJ, Bulek AM, Fuller A, Schauenburg AJ, Miles JJ, Liddy N, Sami M, Li Y, Hossain M, Baker BM, Jakobsen BK, Sewell AK, Cole DK. Madura F, et al. Among authors: miles km, miles jj. J Biol Chem. 2013 Jun 28;288(26):18766-75. doi: 10.1074/jbc.M113.464560. Epub 2013 May 22. J Biol Chem. 2013. PMID: 23698002 Free PMC article.
T-cell receptor (TCR)-peptide specificity overrides affinity-enhancing TCR-major histocompatibility complex interactions.
Cole DK, Miles KM, Madura F, Holland CJ, Schauenburg AJ, Godkin AJ, Bulek AM, Fuller A, Akpovwa HJ, Pymm PG, Liddy N, Sami M, Li Y, Rizkallah PJ, Jakobsen BK, Sewell AK. Cole DK, et al. Among authors: miles km. J Biol Chem. 2014 Jan 10;289(2):628-38. doi: 10.1074/jbc.M113.522110. Epub 2013 Nov 6. J Biol Chem. 2014. PMID: 24196962 Free PMC article.
Systemic administration of IL-33 induces a population of circulating KLRG1hi type 2 innate lymphoid cells and inhibits type 1 innate immunity against multiple myeloma.
Guillerey C, Stannard K, Chen J, Krumeich S, Miles K, Nakamura K, Smith J, Yu Y, Ng S, Harjunpää H, Teng MW, Engwerda C, Belz GT, Smyth MJ. Guillerey C, et al. Among authors: miles k. Immunol Cell Biol. 2021 Jan;99(1):65-83. doi: 10.1111/imcb.12390. Epub 2020 Sep 18. Immunol Cell Biol. 2021. PMID: 32748462
TIGIT immune checkpoint blockade restores CD8+ T-cell immunity against multiple myeloma.
Guillerey C, Harjunpää H, Carrié N, Kassem S, Teo T, Miles K, Krumeich S, Weulersse M, Cuisinier M, Stannard K, Yu Y, Minnie SA, Hill GR, Dougall WC, Avet-Loiseau H, Teng MWL, Nakamura K, Martinet L, Smyth MJ. Guillerey C, et al. Among authors: miles k. Blood. 2018 Oct 18;132(16):1689-1694. doi: 10.1182/blood-2018-01-825265. Epub 2018 Jul 9. Blood. 2018. PMID: 29986909 Free article.
Chemotherapy followed by anti-CD137 mAb immunotherapy improves disease control in a mouse myeloma model.
Guillerey C, Nakamura K, Pichler AC, Barkauskas D, Krumeich S, Stannard K, Miles K, Harjunpää H, Yu Y, Casey M, Doban AI, Lazar M, Hartel G, Smith D, Vuckovic S, Teng MW, Bergsagel PL, Chesi M, Hill GR, Martinet L, Smyth MJ. Guillerey C, et al. Among authors: miles k. JCI Insight. 2019 Jun 13;5(14):e125932. doi: 10.1172/jci.insight.125932. JCI Insight. 2019. PMID: 31194697 Free PMC article.
485 results